New GLP-3 drug significantly slashes both weight and blood sugar levels in Phase III trial. This drug is retatrutide. GLP-3 is shorthand for the fact that it is an agonist of three enzymes: glucagon-like peptide 1 (GLP-1), gastric inhibitory polypeptide (GIP), and glucagon. So it beats drugs like tirzepatide, which only inhibits two enzymes: glucagon-like peptide 1 (GLP-1) and gastric inhibitory polypeptide (GIP). And it's better than semaglutide which only inhibits glucagon-like peptide 1 (GLP-1). So it's the most effective agent, but it's not yet FDA-approved.
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Some had wanted Meta to add a red light on its glasses signaling that the camera was on, and recording people, but now it appears that Meta has decided to pull facial recognition code from its smart glasses. I can't believe Zuck would do that, and suspect that he has something else up his sleeve.
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Why You Should Say 'No' to Being an Organ-Donor. I'm an organ donor. What should be done is to appoint someone to be one's medical power of attorney who can be trusted to make the right decision. People still need a adequate supply of donors, and I would not want to stop being a donor just for this unlikely scenario.
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Can’t Pay Medical Bills? Trump Officials Suggest Getting a Loan. OK, while most of Trump's policies are so much better than the last guy's, I am baffled by this suggestion. I have written to the Trump administration with ideas on how to revamp the healthcare industry. People need an alternative to Obamacare, and although insurance executives might not like it, there is a way to lower prices and improve quality of care for just about everyone. No, it is not universal healthcare, which actually would make things far worse. My idea is not an original one, and I heard about it from reading this book. We need to leverage competitive forces to make healthcare entities fight for the business of the consumer, rather than have the powerless consumer be beholden to what insurance companies want. Doctors have long lost the battle, and are but pawns in the system as patients. I wish Trump and his advisors would listen.
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Genetically modified worms can now produce and deliver drugs inside a living body. Thanks, but no.
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Craig Federighi gets grilled about Apple’s collaboration with Google for Siri AI in iOS 27. Yeah, we're all nervous. Robert Cringely sums up the anxiety quite well.
And Google is worried about agents running wild and breaking stuff. Even Simon Willison was shocked at what Claude Fable was able to do on its own. Not to mention racking up a bill with Anthropic.
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The Trump administration has had enough of electoral cheating, and since some Blue states won't turn over voter rolls, while still expecting to participate in federal elections that will affect the entire country, Trump is having the postal system not be partisan to their scams, and will not deliver ballots. I think this is a great idea. Blue states can defraud their own citizens if they want, but they will not scam the entire nation.
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The UK is taking a page from Korth Korea's playbook. Phones will have to have a government app installed that will enable tracking and snooping.
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Cognitive Endurance as Human Capital. The ability to think persistently, solving a problem to the end, is going to be the new human capital. Well, it always was, until DEI made thinking unnecessary. But yeah, a person able to stick to solving a problem will be valuable indeed.
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Here's a collection of useful tools that you might use. It's too-ly.eu. It's mainly for web developers.
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