19 June 2026

I Solved My Mystery Fatigue with AI. Amy is an AI nerd who gives a masterclass on how to use Skills for Codex and Claude Code to ingest personal health data and use AI to diagnose her mystery condition and reach a diagnosis. And she provides the code on her GitHub and walks you through it. And she's willing to help you get started. Her parting words stay with me – "Nobody is coming to save you. Go and take care of your own health."

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Wait, what? The Most Promising Ebola Vaccine Has Been Sitting on the Shelf for 15 Years. So much of vaccine development depends on money.

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According to data from Retraction Watch, papers by published by Chinese authors between 1996 and 2025 were around six times more likely to be retracted than those by American or British ones. Before the Chinese government banned the practices in 2020, universities often gave researchers publication quotas or paid them bonuses for publication. Authorities have also tried to tackle the problem by cracking down on paper mills and reforming academic evaluation. But reputations take time to repair.
Fool me twice, shame on me.

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How to Invest in IPOs. The best way is to have shares before they go public. I was hoping this article was going to tell me how to do that.

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Towards autonomous medical artificial intelligence agents. This is MIRA (Medical Intelligence for Reasoning and Action). Ugh. Introducing autonomous agents into healthcare sounds reckless. Let's wait on this.

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AI helped diagnose 18 children whose rare diseases had stumped doctors. Now this is where AI can shine. Let data analytics find associations between rare diseases and symptom/sign clusters.

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Very cool. whisperbridge is like StarTrek's universal translator. Real time translation, as if the other speaker was speaking your language.

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This hits hard. My Mathematical Regression. How sad it is to discover that you were a math genius when you were younger, and you hardly recognize your math scribblings from many years ago. Depressing.

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That's what I want to know. Phone Batteries Keep Getting Better. So Why Are We Always Charging?. You think that's bad, how about the Oura ring?

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Key FDA committee unanimously recommends Moderna's flu vaccine. No, not an mRNA vaccine from Moderna. Complete lack of trust.

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Jeff Bezos should stay out of movie making, no?

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N.L. health-care workers got an email promising a day off — but it was only a cybersecurity test. Reminds me of when OHSU did this. Yeah, that wasn't well received.

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Today, on my final day as Director of National Intelligence, I’m releasing never-before-seen communications and documents exposing how Dr. Fauci provided millions in US taxpayer dollars to fund dangerous gain-of-function research at the Wuhan lab, worked with politicized elements within the Intelligence Community to suppress the truth about his actions and hide the virus’ lab-leak origins, and lied to Congress while under oath in 2024. It’s time you know the truth.
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Did ASMLgive their tech to China? They say no, but I thought that one of their machines made it over. It was one of the few things that China could not copy. They needed a working model to study.

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Finding Your Wife/Life Partner in Asia. A Western man's guide to finding your Asian honey. Be careful. It's not as easy as it used to be. This website is not joking. 

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Student loan rates will rise on July 1. If you haven't saved up for college, you really must think hard as to whether it's worthwhile, especially if you need remedial courses at the start.

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Bend is now going to charge a fee to new homes that want natural gas. This was mainly motivated by a 20-something activist. Of course, wealthy people will want to cook with a gas stove. Restaurants don't cook with electric stoves – it just doesn't work. And this will make homes more expensive, which will make them less affordable. Is that the income inequality what you want, Bend? Plus, utility companies are questioning whether it is wise to put extra stress on the electrical grid. And when the power goes out in Bend, as it will do, people will have no way to heat their homes. The amount of the fees was determined by a "social cost" table developed by Obama's EPA, which is subjective. The truth is, climate fear mongering is not working anymore. The teachers still teach it, but people in the real world know it for what it is.

Take a look at the pollution from burning solar panels in Los Angeles. How green is that? 

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California's Billionnaires Tax will make it on the ballot. Let's see how the billionnaires feel who said they wouldn't mind paying the tax. Betcha they thought it wouldn't actually come true.
But the billionnaires won't be alone: California will raise healthcare premiums and also charge a new sales tax on software downloads. All this to support the fraud and grift, since federal money is being withdrawn. 

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Portland City Council continues to gnash their teeth with the lack of money they have at their disposal. Meanwhile, Portlanders plea to get their police back. The city continues to look like crap. And companies like Under Armour will continue to give up and leave.

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18 June 2026

Obesity Accelerates Cognitive Aging. Perhaps it might be more accurate to state that obesity is just associated with cognitive aging. It could be that whatever slows your brain, makes you prefer passive entertainment instead of active and mind-stimulating activities. Just losing weight, such as with a gastric bypass procedure, won't suddenly make you smart. 

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World leaders want American AI. They just don’t want America to be able to turn it off. Such is power. But giving access to a powerful tool like Fable (or Mythos) to everyone would be foolhardy. There is a risk that financial systems might be taken down or classified and compromising information might be hacked and revealed, risking security. There are bad people out there. We're at the point, where such power needs to be granted selectively. America felt this way when no one else had nuclear capability. Now very evil and corrupt states have it. Remember, you may not know what to do with powerful technology, but someone else probably does.

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These are the results of a CNN poll. How embarrassing it must be for them that people watch Fox News more than they watch CNN or NPR. And Newsmax has as much viewership as NYT, ABC, NBC or even BBC. CBS didn't even rate!  I thought it interesting that Joe Rogan has more viewership than the legacy talking heads. I never heard of Aaron Parnas or Heather Cox Richardson.

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Well it turns out the muscles can send an antidepressant signal to the brain through a protein called apelin. Exercise-induced increases in skeletal muscle-derived apelin enhance hippocampal plasticity via apelin and its receptor APJ signaling. Wow, a muscle-brain axis. Always something new.

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A paper came out recently that showed that a hobbled LLM was still able to pass a benchmark Q&A multiple choice test, but when it came to answering the same question in a different context, it couldn't offer the right answer. Sure enough, a study came out showing the medical LLMs that aced medical examination tests still performed poorly in the clinic. Real patient care is different.

Nonetheless, a report was published showing that MIRA (Medical Intelligence for Reasoning and Action) and Google's AMIE (Articulate Medical Intelligence Explorer)—perform at least as well as physicians. The datasets they used were curated clinical conversations taken from EHR interactions. Not quite the same as putting it in action in real life.

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The AI startup Subquadratic launched with a $29 million investment to produce an amazing 12 million token context window model promising faster inference and better accuracy due to their proprietary architecture which scales at less than quadratic order. They apparently use sparse attention, and this is but one of many architectures that have been developed to beat quadratic scaling. This is one to follow.

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Simon Willison thinks that GLM-5.2 is probably the most powerful text-only open weights LLM. It has a 1 million token context window. We'll see – I've been disappointed at the hyper around Chinese models, so I'm skeptical. It's in Ollama, so I can give it a try. Uh, on second thought, maybe I won't.

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Elon Musk predicts a Chinese 'Fable-class' AI by Q1 2027, prompting Tsinghua University's Jie Tang to say it will arrive sooner. I don't doubt Elon – the Chinese are good at copying. They probably had their copying machines on the day it was made available.

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Brave is offering a paid minimal browser called Origin that contains all the privacy protections but without the ad revenue stuff. It's $60 though. Is it worth it? One thing that Brave does better than the rest if fingerprint protection. Instead of having to cut back on the extensions you use and try to be as vanilla as possible, Brave takes the approach of randomizing certain parameters when you access a website to make it look you're someone else each time. But $60? And I can't use my necessary Firefox add-ons? Nah, I'll pass.

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Bryan Johnson is selling his longevity-promoting supplements and medicinals online. This is the guy that was doing home blood exchanges with his young son, so he's definitely, unconventional. Much of the stuff consists of diabetic medications, but I'm surprised that he includes the SGLT2 inhibitors, like Brenzavvy and Jardiance. Man, if you get Fournier's syndrome just because you wanted to stay young-looking, is it worth the risk?

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Google Gemini co-lead Noam Shazeer leaves for OpenAI. Oh well, that's the tech world. People change jobs all the time.

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Your PC Might Soon Demand Proof of Age Before Letting You Browse. This was bound to happen sooner or later. Because some people can't behave themselves. Someone will make a lot of money setting up alternate identities for people. Like in Minority Report.

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I can't believe that some people are still using Apple's Time Capsule. Apple's Time Machine software is useful, but it's slow. The times when you need to use a backup drive is rare for most people, so many don't buy anything more fancy. But it's nice to have that peace of mind. Do it, Apple, and upgrade this software. 

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California seeks to allow kids to 'divorce' their parents without cause. The state continues to be a fountain of moral depravity. There was a time when crap like this would be laughed at, and the sponsor thoroughly ridiculed. But today, people are too afraid to speak up. 

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And Oregon education officials recommend repealing, replacing compulsory school attendance rules. Oregon education is a joke. 

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While the initial budget pitched by Mayor Keith Wilson proposed cuts to Portland Police, Portland Fire & Rescue and Portland parks, councilors were able to include $3 million for urban forestry, and save some police support staff positions and a Portland fire engine. 

They also restored $2.5 million to Portland Street Response, Project Ceasefire, and summer Free for All programs.
Cuts to Police, Fire & Rescue and Parks, but money for NGOs and "street response". And "free" shit. Why are Portlanders getting for their tax money?

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Downtown Seattle lost 30,000 jobs, billions in office value since 2020 payroll tax. Good going, Seattle.
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17 June 2026

Someone created a astronomically-correct solar system, where you can play astronaut. This was vibe-coded during a marathon session with Claude Fable 5. Haven't tried it out, but it sounds impressive. THIS is how one should use artificial intelligence.

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Then there are people who waste tokens asking inane questions on Elbakyan's Sci-Bot, which seems like it's supposed to be a free version of Scite or Consensus or other deep research sites. Is this worth the expenditures on datacenters?

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This is a lesson for all those medical LLMs that claims to have done well on medical licensing exams. It's possible for bots to be pruned (deliberately hobbled) and still pass multiple-choice benchmarks, but when the question is asked directly, bots "often fail" and the correct answer won't be highly-ranked in the output. They call it the Benchmark Illusion.

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Is Apple following the same strategy that Microsoft did when they came out with Universal Windows Platform? I don't remember that campaign from 2015. I can see the appeal, but it's a technical nightmare, and may slow things down. We'll see.

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In this way, the emergence of today’s AI health products remind me of the rise, in the 2010s, of ride-sharing services such as Uber and Lyft. The taxi industry is heavily regulated, making it difficult for new players to enter the market. Yet by skirting and at times ignoring those rules, ride-sharing companies were able to acquire a critical mass of users in a short period of time. Pretty soon, governments had little choice but to adjust their laws to match what had by then become the status quo. The same pattern could end up playing out in medicine. Will regulations meant to ensure that medical products are safe and effective remain in force? Or will they instead be weakened or removed to clear the path for tools that everyone is already using?
Interesting perspective. Maybe the FDA will just throw up their hands and craft law around the usage.

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Amazon almost killed Best Buy, yet they survived. I still go to Best Buy and am glad they're still around. How did the CEO do it? Basically, he refused to give up, and chose to compete with Amazon leveraging their own advantages.

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You can start a business renting EV chargers. This is like buying vending machines and making money off the convenience. Or renting parking space. Cool. But be prepared to sustain damage. This kind of business probably doesn't work in Blue cities. It probably works in Japan or South Korea or Singapore – places where people respect property. Not in the U.S.

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Doom Loop. Under Armour is moving out of Portland. This is no small company. The number of employees who will lose jobs isn't reported in the article. Tick tock, Portland.

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Oregon cities rank lower in bike friendliness. Man, can't Oregon win something?

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Seattle City Light eyes biggest bill increases in recent memory. Well, with all the wealthy people leaving the city, someone's gotta pay, right?

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16 June 2026

Earth's underground fungal network is so massive, it would span 10% of the Milky Way. This refers to the extensive mycorrhizal network that many mushrooms are associated with. This is why honey mushrooms are the largest single organism on earth.

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There's a website where you can track stock trades on Congressionals. The website is here – GovGreed. Here's how they apparently profit from insider trading. It's like the Unusual Whales website.

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SpaceX is buying Cursor. Or rather it bought an option to purchase the company for $60 billion later this year. I'm really surprised that Cursor hasn't already been bought out already.

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Apple's 2028 iPhones to Use 1.4nm A22 Pro Chips. The late 2026 and 2027 iPhones will use 2 nm chips.

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The mathematical secrets hidden at the heart of Barcelona’s Sagrada Família. It's all numerology stuff. Still interesting, though.

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One fallout of generative AI and deepfake photography is that you can't trust any photo at face value anymore. It's a different world now. Images are just images. Just what hits your eye.

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Fabrice Bellard is the unsung hero of the Internet. Most have used his work, but he is almost completely unknown.

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I just found the name of the fallacy that the Left likes to use to bolster their arguments and make them feel self-righteous. It's the Motte-and-Bailey Fallacy. Like if you object to reparations then you must be in favor of racial injustices. Or if you object to men using women's bathrooms then you must object to transgender human rights. Things like that

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15 June 2026

How Many Elementary Particles Are There, Really? 17 that we know about. But there may be more.

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With the next update, ad blockers will stop working in the Google Chrome browser. Not that you needed another reason not to use Chrome.

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Americans Aren’t Money Savvy, and They’re Only Getting Worse. This is the New York Times, so you can never be sure about the journalism, but this story I believe. Especially certain demographics. The only reason we don't see more serious destitution is because of government subsidies. It's not just investment knowledge but just basic economics. And I suspect must of these people run the City of Portland's government. 

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We know that P-glycoprotein is the cellular pump that expels poisons out of cells. For example, it's one of the reasons why cells are resistant to chemotherapy. But P-glycoprotein also pumps out harmful amyloid-β out of the brain so that it can be cleared. Recently, it was shown that a copper-dependent protein, Cu(ATSM) restores levels of P-glypcoprotein, reduces levels of amyloid-β and restores long-term spatial memory in mice.

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Stress is everywhere. San Andreas fault reaches highest stress level in 1,000 years.

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WA falls to 31st in national education ranking. But hey, Oregon is 44th. I can't imagine why. 
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Firefox 152 will add JPEG XL support. That will be nice.

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Seattle is setting up "protest zones" and hopes that protestors will respect those boundaries. Sure, sure.

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The most dangerous neighborhoods in Portland. They're where you'd think they would be.

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More Than One in 250 Biological Girls in Oregon Between 2016 and 2023 Were on Testosterone by Age 17.
Oregon harbors some sick and horrific medical practitioners. How this was allowed to happen is absolutely horrific.
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Portland Public School’s Failed Equity Policy Shows No Evidence, No Results. You cannot guarantee equal outcomes.

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OHSU and Legacy get new CEOs. Legacy is in need of a facilities makeover. Parts of Good Samaritan Hospital really look decrepit and in disrepair, like some communist-era facility. It's really fallen below the Providence system, that's for sure. 

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14 June 2026

Not much to comment on today. 🤔

Here's a video commenting on the unprecedented move to take Fable 5 offline for the world. While I do think that there are some peopke who shouldn't have access to something that powerful, who am I to say. There are legit uses and some could put it to beneficial use. But the author is probably correct – investors may think twice about AI investments in the U.S. if stuff like this can happen. But it would help to tighten the jailbreak guardrails before releasing it again.

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How to Earn a Billion Dollars. Paul Graham riffs on one of AOC's latest dumb comment about how you can't actually earn a billion dollars. Her small mind can conceive of how this could happen. Great essay.

How much of Elon Musk’s wealth comes from government help? Virtually all of it. This isn't welfare, though. It's getting seed capital to get a business off the ground. I'd say Elon has been quite successful at doing that. There is risk and it could have gone a different way. 

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Our study found that PEDs other than the iPhone 12 have magnetic susceptibility and thus have the potential to inhibit lifesaving therapies. 
Keep these devices at least 2 cm from your pacemaker or ICD.

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No class. Stanford students boo Satya Nadella at graduation. Don't expect venture money from Vinod Khosla.

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13 June 2026

Why Yann LeCun is Spending $1 Billion to Replace LLMs with JEPA. JEPA is Joint Embedding Predictive Architecture

JEPA...focuses on modeling the physical world through abstract representations, drawing inspiration from how humans, particularly infants, learn by observing and interacting with their environment.

You can listed to Le Cun explain it all himself in this video.

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Anthropic's Fable suddenly went offline. Supposedly the federal government didn't want it to get into the hands of foreign entities. But maybe there's an additional explanation. Apparently Fable was jailbroken by a security researcher, Pliny the Liberator. And pretty quickly, too. So if it could be done quickly, imagine what China or Russia could do. Better to take it offline for now.

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To maximize the lifespan of your Apple product, it's best to set the maximum charge at 80%. Use Apple's smart charging program to orchestrate the charging schedule.

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FDA Approves ‘New’ sunscreen ingredient bemotrizinol (PARSOL Shield) used in Europe and Asia for years. But what I'm seeing as an ingredient in the Korean and Japanese sunscreens is avobenzone. The problem is that it is often paired with ingredients such as homosalate, octinoxate, oxybenzone, and octocrylene, which are potential endocrine disruptors, with potential estrogenic stimulatory effects, and these agents are absorbed through the skin. I see that even Neutrogena sunscreen has homosalate. Two Asian sunscreens that seem to be safe are Beauty of Joseon Relief Sun: Rice + Probiotic and Round Lab Birch Juice Moisturizing Sunscreen, which you can get on Amazon.

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The Chinese are using plastic heads in their Teslas to fool the onboard AI that monitors their gaze. Tesla will probably upgrade their AI to watch out for this. Until then...

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Someone asked Claude who is most likely to be Satoshi Nakamoto. I have no basis to agree or disagree with Claude.

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General-purpose large language models outperform specialized clinical AI tools on medical benchmarks. This is embarrassing. There are AI models like OpenEvidence and UpToDate Expert AI that specialize in answering medical questions. But compared with general purpose frontier models, they were inferior. That's not going to instill investor confidence, is it?

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But of course! Oregon lawmakers demand that the Feds allow mail-in voting. They need mail-in voting to win. Listen to Michael Knowles:
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Oregon's population is getting older as younger wage-earning segment move out of the state. It's not good for the state's economics to have more old people in the state. They don't bring in money and they don't spend as much. But can you blame hard working people for not wanting to stay in Oregon?

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12 June 2026

Scientists remove the extra chromosome that causes Down Syndrome. Scientists from Japan were able to use CRISPR-Cas9 technology to target just one allele of in a trisomy 9 culture of fibroblast cells. They were successful in about 13.9% compared with only 0.42% of controls. They did observe small insertions and deletions that were too small to detect on the usual G-banding staining, but the significance of these is unclear. This is a start, and should it become more effective, it could transform the lives of children with Down's Syndrome. Paper here.

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Major depression may be associated with genetic changes that can be detected in blood leukocytes. The genes involved are those relevant to synapse biology. This suggests that the cause of depression is indeed likely genetic. Paper here.

And speaking of depression, OHSU researchers link elevated brain levels of serotonin to tinnitus. The study was done in mice, so we don't know for sure if they experienced ringing in the ears, but the scientists think so. 

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CoolA working model of the universe, in your browser.

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Oh no! Scientists found that glucosamine, a supplement taken by 40 million Americans for joint pain is associated with 25% faster progression to Alzheimer’s in people with early memory decline. Turns out that it causes glycosylation of brain tissue (similar to diabetes mellitus).

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Gwern has an idea to develop a guardian angel LLM. Interesting idea. Maybe he can market it.

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Script kiddie's agent bankrupts him. This is why I don't trust autonomous agents.

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More than a quarter of private colleges are at risk of closing. Even in Britain, universities are closing. What could be the cause? The authors skirt around the issue. Declining birth rates. Declining international students. But how does that explain the situation in Britain? Oh, they blame far-right influence:
Universities are not popular. They are under increasing assault from the populist right as ridiculous factories of so-called “woke” ideas, and the vast debts that have been placed on young people have come to seem like less and less of a good deal as the terms have changed. Two-thirds of students tell YouGov that they think their tuition is poor value for money: only 6 per cent of voters said they wanted more university spending in one 2024 poll. The so-called “graduate premium” of higher earnings for workers with degrees does still exist, but at 24 per cent among young people it’s not what it was.
Yeah, I think the educators are not what they once were.

But some students are finding a way to get the university education they dreamed of, even if they don't go in through usual channels.

And here's Oregon: Most of Oregon’s State Teacher Prep Programs Still Get an F in Reading Instruction. Take a look at the teachers. Whoa, they sure don't look like the teachers I had when I was growing up. 😬

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In pursuit of beauty, Chinese women take unapproved measures with unexpected consequences. Those Chinese doctors should be jailed for this. How do they live with themselves?

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Oregon pulls out of Great American State Fair in Washington, D.C. Most of the poll takers do not support Kotek's decision. How petty our leaders are. 🙄

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11 June 2026

New GLP-3 drug significantly slashes both weight and blood sugar levels in Phase III trial. This drug is retatrutide. GLP-3 is shorthand for the fact that it is an agonist of three enzymes: glucagon-like peptide 1 (GLP-1), gastric inhibitory polypeptide (GIP), and glucagon. So it beats drugs like tirzepatide, which only inhibits two enzymes: glucagon-like peptide 1 (GLP-1) and gastric inhibitory polypeptide (GIP). And it's better than semaglutide which only inhibits glucagon-like peptide 1 (GLP-1). So it's the most effective agent, but it's not yet FDA-approved.

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Some had wanted Meta to add a red light on its glasses signaling that the camera was on, and recording people, but now it appears that Meta has decided to pull facial recognition code from its smart glasses. I can't believe Zuck would do that, and suspect that he has something else up his sleeve.

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Why You Should Say 'No' to Being an Organ-Donor. I'm an organ donor. What should be done is to appoint someone to be one's medical power of attorney who can be trusted to make the right decision. People still need a adequate supply of donors, and I would not want to stop being a donor just for this unlikely scenario.

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Can’t Pay Medical Bills? Trump Officials Suggest Getting a Loan. OK, while most of Trump's policies are so much better than the last guy's, I am baffled by this suggestion. I have written to the Trump administration with ideas on how to revamp the healthcare industry. People need an alternative to Obamacare, and although insurance executives might not like it, there is a way to lower prices and improve quality of care for just about everyone. No, it is not universal healthcare, which actually would make things far worse. My idea is not an original one, and I heard about it from reading this book. We need to leverage competitive forces to make healthcare entities fight for the business of the consumer, rather than have the powerless consumer be beholden to what insurance companies want. Doctors have long lost the battle, and are but pawns in the system as patients. I wish Trump and his advisors would listen.

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No, Dr. Brian Druker is not an ivermectin shill.

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COVID-19 was a scammer's dream, wasn't it?

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And Google is worried about agents running wild and breaking stuff. Even Simon Willison was shocked at what Claude Fable was able to do on its own. Not to mention racking up a bill with Anthropic.

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The Trump administration has had enough of electoral cheating, and since some Blue states won't turn over voter rolls, while still expecting to participate in federal elections that will affect the entire country, Trump is having the postal system not be partisan to their scams, and will not deliver ballots. I think this is a great idea. Blue states can defraud their own citizens if they want, but they will not scam the entire nation.

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The UK is taking a page from Korth Korea's playbook. Phones will have to have a government app installed that will enable tracking and snooping.

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Cognitive Endurance as Human Capital. The ability to think persistently, solving a problem to the end, is going to be the new human capital. Well, it always was, until DEI made thinking unnecessary. But yeah, a person able to stick to solving a problem will be valuable indeed.

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Here's a collection of useful tools that you might use. It's too-ly.eu. It's mainly for web developers.

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10 June 2026

Voyager is a fascinating tool – like Star Trek come true. You can call people in other countries, and through Translate GPT, get instantaneous translation. This should get more publicity. Of course, it uses token costs, so I can understand why these guys don't want too much traffic.

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The enthusiasm regarding the capabilities and usefulness of large-scale AI in health care is understandable. Nevertheless, the massive environmental, economic, and social costs should be considered while developing and using them. Improving the performance and clinical value of AI without overlooking its costs is important for balancing the sustainability of large-scale AI and its usefulness in health care.
People are already complaining about how much datacenters spew out in pollution. Wait until the healthcare industry starts getting seriously involved.  Yikes!

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iOS 27 features we didn’t see onstage. Minor things, mainly UI changes. Just when I started learning where all the camera app controls were, I probably have to relearn them.

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The first and unsurprising observation is that being useful on these tasks requires your agent to have context, which means: relatively unrestricted access to your private data. You know about your invitees’ availability because they texted it to you. You know about Mike’s allergy because you’ve talked about it with him or jotted it down somewhere. (This could mean iMessages, email, contacts, or personal notes.) Re-entering all of this data into an agent would be annoying and time consuming and the whole point of an agent is to save you time. The winning personal assistant doesn’t win just because it’s smart: it wins because it “already knows” the things you need it to know, like a personal assistant who sits next to your desk.

Allow me to dig into the details just a bit deeper. The agent might scan your messages database to learn the parameters needed to schedule your dinner. Or, in a more token-efficient system, it might read your messages continuously and store a “memory” that distills useful facts that it might need later. Both can be functionally equivalent, but one produces an artifact that may be highly sensitive. And keep in mind that the set of facts that might be useful is very broad. For example, Mike’s allergy is one of those facts. But there are many others. For example, the private conversation you had where you discovered that Mike was having an affair is potentially another fact that could be stored or accessed by a system. Memory or not, this data will all be within the agent’s view, and you’ll have to hope that it knows which one to operate on.
All of a sudden, the AI agent knows about your confidential text messages and incorporates that into its memory, and things you might regret having sent once is not part of the agent's permanent memory. OpenClaw can leak your secrets, too.

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We see Siri not as a separate chatbot, just an unintegrated place you go and chit-chat, but rather as an integral, conversational tool that you use in the moment, deeply integrated into your experience.
Who needs this stuff, really? This is just like when doctors have AI software foisted upon them that they don't really need.

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Speaking of doctors, here's a radiology article where they looked at AI models. They refer to early models like Claude 3.5 Sonnet as a vLLM. I did a double-take. That model is not a vLLM (virtual LLM). I think what the authors are thinking of are multimodal LLMs. And the abbreviation for vision LLMs is VLM.

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GLP-1s appear to protect against cancer. Researchers are trying to figure out how. This is actually not a new observation. I suspect that by getting people to lose weight, cancer risk declines. But what mechanisms are involved are still worth exploring.

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There's a lot of online postings about Claude 5 Fable, which is the consumer version of Mythos. Someone thinks they have found the leaked system prompt. And Fable will apparently balk when you use the word "cancer" in your user prompt. Violates guardrails, or something like that. Biosecurity risk, they call it.

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Landmark German ruling declares Google's AI Overviews are Google's own words and makes it liable for false answers. So now what will Google do? Guess they'll have to redirect the user to the underlying website after all, instead of keeping them on the Google site with their AI-generated summary, so you don't have to actually go to the website and give them traffic.

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New research links even low alcohol consumption to cancer, heart disease, and premature death. You might be able to still have some alcohol, though. One drink of wine or one beer daily might be OK. Two drinks – definitely not. The less, the better.

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First Human Receives Experimental Therapy to Reverse Cellular Aging. The drug is ER-100, which is an adenovirus vector that delivers genes coding for the Yamanaka factors, Oct4, Sox2, Klf4. The adenoviral vector is activated with intravenous doxycycline. Sounds cool, but it sounds too simplistic. Can't believe that reversing age will be that simple. We'll see. 

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The consequences of relying on AI for accurate news. What happened was that users eventually lost the ability to distinguish between real and fake news.

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SignalTrace will add iPhone, AirPod, and Smartwatch Trackers to License Plate Readers. Holy crap! You'll need to turn your car into a Faraday cage. This is like Flock on steroids.

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The Nerdy Escorts Cashing In On Silicon Valley’s AI Boom. We call it prostitution – Silicon Valley nerds called is VaaS (vagina as a service). Makes sense. Boy, the money those girls can make! But I bet a lot of their clients are H-1B visa holders! 🤣 Money is money, though.

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Wow, once your private GitHub repo turns public, information is scarfed up 6 minutes. People watch for these things.

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A Proof on the Computational Complexity of the Traveling Salesman Problem: Why P ≠ N P. Someone claims to have found proof of this Millennium Prize problem. Such a short proof. Two pages? Can't be that easy, right?

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Some scientists are upset that there is now some oversight over what research gets approved for funding. Sure, some research that sounds like it might be pointless does sometimes lead to major advances. But that's not the kind of silly pointless research that is being cut. It's the DEI woke stuff.  

Speaking of which, I saw this article recently: Over 1 in 250 Natal Girls Were Taking Testosterone By Age 17 in Oregon, From 2016 to 2023. The proponents still think it's rare, but admit that it has increased over the years. But the graphs tell the story. Here's one:
Cleveland Clinic has decided to end pediatric gender-affirming care, just as Texas Children's Hospital did last month. This is one of the main reasons why the public holds the medical profession in low regard (the other reasons being the COVID vax and saying that "white supremacy is a lethal public health issue"). Monstrous.
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Seattle is going to ban datacenters for a year. They already have datacenters in the Belltown area.

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PacificSource Health Plans laying off 130 amid rising health care costs. Without continued federal government support, Obamacare is collapsing.

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Typical Portland household could pay extra $700 annually with latest tax, fee hikes. So glad I don't live in Portland.

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