8 October 2026

The response from yesterday's OpenAI release of math preprints was tremendous. You'd almost think that mathematicians were telling AI developers to ask permission before working on math problems. Clearly a lot of material was dumped that will require scrutiny. Alex Kontorovich was impressed by the output. But there is much anxiety and uncertainty about what it all means, especially to crypto and security. I'm hoping that some smart humans will be able to sift through all of it quickly enough before a vulnerability is exploited.

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Oh brother. Female AI agents ‘paid’ less than males, study finds. Unconscious bias at work? Or much ado about nothing?

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President Donald Trump will award Elon Musk and other leading American innovators the nation’s highest honors for scientific and technological achievement. I'm not seeing Sam Altman or Dario Amodei among the awardees. But I'm also not seeing Ashish Waswani (and co-authors), Demis Hassabis, Ian Goodfellow, Ilya Sutskever and Yann LeCun. And why just Sergey Brin and not Larry Page? These guys made it happen so that the business folks could be successful. The geeks need to be rewarded, too.

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Cops can break into locked iPhones. Consumer devices are not military-grade.

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Ecosia search engine wanted to be all-European, but finally admits that Chinese models are better. So they're ditching Mistral for Chinese open-weight models. They should check out DeepSeek V4.1 Flash.

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Adults don't want to have children. Not finding the right partner is one of the top reasons. I can understand that. The pickings are indeed slim. But people who shouldn't be having them are having them anyway.

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Claude 5.5 Opus can bring invisible cities to life. The key is a good prompt and giving it sufficient time. And a good budget, too.

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Some think that Alex Honnold has no fear. Turns out he has lots of fear, but he has learned how to manage it.

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This is a common experience when using search engines to find stuff. I'm finding myself resorting to an AI assistant more often.

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COVID-19 dropped out of the global top ten causes of death. How bad was COVID-19 really? Was it all just the virus? Or were people ill with something else along with the virus? Or was it the way the disease was managed? I know far more people who got sick with the virus who were just mildly ill and recovered uneventfully.

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How to de-index your site from Google. If that's what you want to do.

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Medical world models are starting to be a thing. Imagine that you can model the patient state of someone with pancreatic cancer, including medical images, clinical text, physiological signals (such as from sensors), EHR events, molecular/cellular signals and procedural imaging, and simulate disease trajectory. Then a physician could see the consequences of a clinical decision. Real-world interventions would be fed back into the model.

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7 October 2026

How to Limit What Apple’s New Siri AI Can Access in iOS 27. There seems to be a lot of interest in limiting Siri. I still don't want Siri to access my stuff.

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Anthropic quietly builds biolab run by Claude AI. As long as it's used for good.

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Even the NYT knows that we will need AI in the future. Or SI.

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Hard to believe this sci-fi short by Ted Chiang is from 2000. Very prescient.

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Man discovers his parents’ coffee machine used 1TB of data in 10 days. What's the coffee machine doing? Mining crypto? Acting as a residential proxy?

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Creating Fake People is a Terrible Idea. Modeling human metabolic systems can be used for good, but that's not what this article is talking about. Duplicating a person as an avatar is creepy and uncharted territory. As AI tech gets better, it's going to be worse, especially if the underlying model develops some semblance of consciousness and a sense of self-awareness.

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Here's an AI application I can get behind. An amateur researcher discovered an unknown distant planet using Claude Code.  Downloaded a dataset and did some data analysis. Then verified his hypothesis prospectively on observational data. Kudos to this person.

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NVIDIA Research Finds AI Agents Become Less Safe When Using Tools. Apparently all the safeguards you build in don't apply when agent use tools autonomously. The careful guardrails in prompts that were set up, get "diluted" by context the more the agent uses tools. Yeah, that's not good.

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The scariest thing about gray-market peptides is how little we know. But people will use them anyway. As long as it's self-medication, I'm not too concerned.

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The keys to the Internet change on October 11. Are you ready? Cloudflare is making changes to its DNSSEC protocol. It should be invisible. I have my DNS resolver set to 9.9.9.9 and it's compliant. 1.1.1.1 will definitely be compliant. Check yours.

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Daylight Savings Bill dies. Although I hate changing clocks twice a year, I want permanent Standard Time. The U.S. has tried permanent DST twice and it didn't work and it was changed back. It's not even good for you. If it were permanent Standard Time, maybe Tom Cotton would have advanced it. Congress seems to always screws things up. 

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Don't you hate when companies shove chatbots into their websites, because it's de rigeur? This is what can happen when you do and aren't careful.  Because there are people who will always want to screw around and see what happens. You can't risk that.

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Hardware is catching up. Local AI is real now. And this is with only 256GB of unified memory. Can't wait for what 512GB will do.

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OpenAI just release 722 new math manuscripts of their discoveries. Here are preprints. Human mathematicians aren't going to keep up with this. No wonder the panic.

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It doesn't take much to get you banned from Reddit. I got banned posting truths about the COVID-19 vaccine. Badge of honor.

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This is why the Oregonian banned comments. Here's an article on their X feed: Several Portland restaurants and bars are closing, citing tariffs, rising costs, COVID-19 fallout, and retirement as key factors. No, it's not Trump's tariffs. You can't blame COVID anymore, geez. Retirement? C'mon. Yeah, it's rising costs, but be specific. It's all the taxes and having to pay so much minimum wage. Energy is expensive because of carbon policy and taxes, too. The comments reveal the truth the O can't hide.

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6 October 2026

The Sound of Silence: What Your AI Agent Does Not Tell You. Ha, seems like this guy just discovered the importance of having a large context window. Or the value of system prompts. Yeah, when you just have a conversation with an agent, it will soon forget what you talked about before. The oldest inputs fall off and are replaced with new inputs. If you want it to remember certain instructions, they must be put into a system prompt which gets loaded every time.

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Mistral debuts Large 4 ‘Le Chonk', a 1-trillion parameter text output model. Everyone has been talking only about American and Chinese models. How we've forgotten that France has a model, too. Now, Mistral announces "Le Chonk" with a trillion parameters. Yeah, we're not going to be downloaded that beast on our machines. It seems to be at pace with the best of the Chinese models, but the Chinese models are smaller. Wake me up when Le Chonk loses weight or gets much better.

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Effects of creatine supplementation with and without exercise and diet intervention on body composition, cognitive function, and markers of health in middle-aged and older adults. So you don't have to exercise to get the muscle-retaining benefits from creatinine, being a senior. I used to find it hard to take creatine. The large capsules or the inconvenient powders were unappealing. But I've discovered the chewable tablets by Bodytech. They're quite tasty and easy to use. 

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iPhone Duo display confirmed to peel off on purpose. Wow, the matte nano-texture screen covering on the iPhone Duo is replaceable. It's there to preserve the crease-free hinge. Very nice. Apple thinks of these things, and now others will probably copy this. 

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For Robertson, currently studying for a Ph.D. in quantum-safe cryptography at the University of Amsterdam, the problem is even more acute. She has seen all of her mathematics colleagues turn to using LLMs intensively in their research, with many maxing out their Pro subscriptions, and some even spending thousands of euros on additional tokens: “And these are Ph.D. students who don’t have thousands of euros,” she added.

Robertson said that there are colleagues who feel coerced by the tech giants, with the likes of OpenAI announcing in July that it is giving away 100,000 free licenses to its frontier models for researchers in academia. And there are other colleagues who feel they simply have no choice: “If you don’t work at the rate at which you could work with LLMs then you will be behind your peers who will be applying for the same jobs as you.”
Mathematics has changed irreversibly. Now, mathematicians have to get access to the best frontier models, and learn how to design prompts.

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Newborn Genome Sequencing To Be Offered In Oregon. It's just going to be available at Peace Health and OHSU, but Providence and Legacy will probably add it on, too. I don't think it's something every baby should have done. Only for those where you suspect an abnormality, and want to get prepared. The asymmetry in this information is clear: there is no mutation that is good news. The only good news is no harmful mutation, but many mutations are bound to show up. When we don't know what the implications of the mutations are, we just call them polymorphisms – just a variant of some sort. But it's not worth the anxiety and heartbreak, unless there is a mutation for which you can take action. Which is very rare. And the action is usually to remove some organ as a precaution.

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If I were Adobe, I'd be a little concerned:
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5 October 2026

Florida woman used Claude as a diary, then Anthropic reported an entry to police. This is what happens when you use technology you don't fully understand. This haas already happened with Google searchers. People haven't learned. These services are not private. Only local model usage, or cloud computing with zero data-retention policies can give you this. 🙄

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Your car is a smartphone on wheels. Here's who's listening. Today, it's just vehicle telemetry. But soon, they will listen to conversations so that certain words will trigger AI agents. This is not the future I wanted.

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15 years after his passing, nobody is ‘The Next Steve Jobs’. Certainly not Tim Cook. Probably the closest person is Elon Musk, in terms of boldness of vision, and refusal to accept someone else's definition of "impossible". Steve grew up at a time when it was still common to uphold the old hippie ideals, and his love for the Whole Earth Catalog seems quaint. We don't think like that now. Today's people are more defined about what they hate. They hate Nazis, fascists, racists, sexists, etc. You have to have the "correct" political views to eat at a Portland restaurant now. 
And rich people. Here's two of Portland's city council, wanting to inflict financial pain on rich people. And they assume everyone is cool with it. Check out what happened in Nashville recently. Their symphony was about to shut down because of financial struggles. But Oracle decided to help out and gave them a lifeline. Now they can have a nice program. See what billionaires can do? But this will never happen to Portland. The city can go down the toilet and no one will come out to rescue them. We so badly need a Steve Jobs-type for Portland.

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Your Right to Privacy Doesn't Disappear When You're in Public: Defenders of Flock-style surveillance systems argue that people “have no reasonable expectation of privacy in public.” The authors think they're wrong, but in reality you don't have a right to privacy just being out in public. On your own property, yes, but no where else, except in private areas, like restrooms, dressing rooms, etc.

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Things that Apparently Cause Cancer. Great article debunking a Harvard study that linked cancer incidence with being close to a nuclear facility. It appears that their methodology makes Costco look bad, too.

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Honda is testing a system that charges EV trucks while their driving. Like Qi charging, except the whole road is the charger. This is crazy and way to expensive. Just make better batteries, already.

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Why aren't people using Lemmy?  I looked into Lemmy as Reddit is becoming more closed off. But wow, you can see the difference in quality. Lemmy seems to be just populated by high school boys. There's very little intelligent conversation. At least not on lemmy.world, the largest of the lemmys. I guess I'm going to be on Lobsters, Tildes and HN exclusively.

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The further degradation of the city. Multnomah County advances plan that would extend East County ambulance response standards to 15 minutes. Every minute counts with cardiac arrests and strokes. Waiting 15 minutes is unacceptable. We're going to see a lot more failures. 😪

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4 October 2026

Lung cancers can use two different mechanisms to evade KRAS-inhibiting drugs. RAS inhibitors in lung cancer work differently from the multi-RAS inhibitor used in pancreatic cancer. Resistance has been an issue with targeted therapies for a long time, which has been challenge. The long-term good luck that was seen with imatinib against chronic myelogenous leukemia has not panned out in most other diseases. But understanding how breakthrough occurs is the first step in understanding how to improve these drugs.

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Five Things I Learned in Hiring a Financial Adviser. There's more to what a financial planner does than just pick stocks for you, or manage your portfolio. It helps to have someone evaluate your estate planning and tax situation as well.

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This morning there's been several articles about college graduates and their prospects afterwards. Here's one that questions whether you need to go to college in the first place. Fox News says that more Gen Z college freshmen are quitting school early and moving back home with mom and dad. Here's one that suggests that the quality of a college education has been declining.  And a Gallup poll indicates that a record-low (31%) say that a college education Is 'Very Important'. 

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Here's a report that indicates that an increasing number of households are spending on AI, but only about 2% of households are paying for it. This suggests that there's still plenty of upside. Then they have to decide whether they'll put up with datacenters after all.

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Tesla's robotaxis won't operate at night because they have no Lidar. Waymo uses Lidar and operates 24 hours/day. But Musk doesn't believe in Lidar for some reason. Even Rivian uses Lidar.

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Mote is a website that lets you have private chats where nothing is recorded (by them) and it's all private. Don't we already have encrypted chat? Can we trust these folks? I can't find any information about who set this up.

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Property managers in Portland are finding that it's not safe to do their work now. And if tenants declare apartments to be off-limits, this is how you start to get no-go zones in your city. This is what Portland is becoming.

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3 October 2026

If you bought an iPhone 18 Pro Max and cellular communication stops working, you need to get a replacement phone. If you haven't lost service yet, you should update your phone ASAP. But if it's already gone, you need a replacement phone.

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OpenAI safety leader quits, warning AI company’s culture is ‘broken’. Well, that doesn't sound good. These days, I can't get too excited when people quit because they don't like the company culture. He wasn't a good fit, that's all.

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Singapore builds most accurate clock ever, leaves US and China in dust. I think what he have is already pretty good. A second off in a 6 million years? Good enough for most things, I'll wager. Singapore's clock is a second off in 260 billion years. Well good.

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There's a rumor that Robert X Cringely has died. That would be sad. His columns entertained me for many years. He seems to have encountered a lot of bad luck in the past decade or so. He'll be missed by dotcom-aged nerds and geeks.

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Wow, I never thought about this. Updates to Full Disk Access in macOS. Several of my apps already request and are granted full disk access. But with the trend to include AI agents to do this and that, there is a danger that some of these autonomous agents will pull stuff in the course of their activities that are not something that the developer necessarily planned on, but would not be something I would want exposed, like financial or personal records. So Apple is making it harder for agents to get Full Disk Access, which is good.

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Google AI Plus and free users are losing access to Gemini models, and it's happening very soon. Oh well. It was great while it lasted.

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For years, AI’s builders said that their technology would create an abundance of cheap stuff. ...Many of AI’s builders, including Dario Amodei and Altman, anticipated that the plunging price of superintelligence would be so dramatic that millions of jobs would disappear.

But AI’s reality is the opposite of the forecast. AI has not caused mass unemployment in a period of plunging prices. Instead, everybody has a job, and everything is getting more expensive.
Because everyone is using AI to create new things, and all those new things come at a cost. It was too naïve to say that things would be cheap. Using AI tools is expensive. It's just Jevon's Paradox. But I am confident that costs will eventually lower as efficiencies kick in.

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Cities keep shelling out taxpayer money for sports stadiums, yet the economics almost never makes sense. Someone send this article to Keith Wilson and Tina Kotek. Forget the Blazers and paying for the MODA Center. Portland can't afford it. Stuff like this is for wealthy cities, and Portland is not that anymore. You've let the city run into the ground, now experience the consequences. Keeping the Blazers is just pretending that we're still the same old Portland. We aren't. It's not like the Bud Clark days anymore. This is the gift of socialism – poverty.

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Oregonians are discovering that EVs aren't the sensible car to drive. Get a hybrid, man. It's really the best. EVs only make sense in places like the Bay Area.

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2 October 2026

Why have the Chinese been so willing to share the weights of their advanced models?  Good question. Some of their open-weight models rival American frontier models, which they probably should since they were probably distilled from them. But I'm glad they are. So far there don't seem to be any hidden back doors, although some of them still require that some of your data goes back to China. Gotta be careful. 

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Frog and Toad and the Increasingly Capable Machines. How to understand the Huggingface break-in affair, explained like you're 5.

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Defrauding Federal Programs Can Be Ticket to Being a Billionaire. Yeah, this is why I opposed single-payer healthcare under control of the federal government. They can't even detect crap like this.

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Used processor leads to game ban. There was a reason why those CPUs were cheap. So game software checks your CPU ID now, and if it's on a blacklist, it will not run. This was a used AMD processor, a Ryzen 7 5800X3D. Wow, too bad for the guy that bought it, but apparently it was just one computer system with the banned CPU.

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Jev is getting a lot of attention now. It's the latest craze, like Claw and Moltbot was six months ago. It's basically a classifier, but it's biased. When asked about truly random decisions, its output does not produce a random distribution. That makes it less useful than the hype. Maybe they'll fix it.

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This is amazing. Planets observed rotating around a distant star 133 light-years away. It's HR 8799 in Pegasus.
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There's something else to complain about datacenters: e-waste. Turns out that you have to replace the hardware fairly often, because newer and better stuff comes out all the time. What happens to the old stuff? We need to recycle it.

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Someone else is leaving Reddit because they're shutting down RSS access. I'm already planning a migration to lemmy.world. I bet that Lemmy will see a big influx of Reddit users.

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Pallet CEO fears Seattle’s homelessness response going ‘backwards’. As Seattle runs out of other people's money, this NGO is having to shut down. Homelessness has become a business model for the Left. Hopefully this means we'll see less of those unsightly tool-shed homes. Seattle is running out of money to pay for homeless services. When you take into accouint community safety and violence prevention, food and nutrition programs on top of homeless response, it adds up to around 12% of the $2 billion general fund. 

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1 October 2026

Cannabis use is associated with increased risk of violence. Even more evidence. Do we really need this in America right now? One of the selling points of cannabis over alcohol was that it wouldn't make people as violent, and instead, make them mellow. That didn't turn out to be the case with the higher potenct weed.

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I saw that both semaglutide and tirzepatide can activate brown fat in mice, which really just means it made the thermogenic brown fat work harder. It's also a mouse study, and adult humans don't have much brown fat. But formoterol can increase energy expenditure without activating brown fat, through activating beta-2 adrenergic receptors. One caution is that drugs that stimulated beta-3-adrenergic pathways, which activated brown fat, also had adverse cardiac dysrhythmia side-effects. So although this worked in mice, it's not an automatic that this will work in humans.

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Google Grapples With Employee Skepticism About New Gemini 4 Model. If even your own employees are not convinced it's that great, what does that say?

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Experimental Drug Reverses Paralysis and Vision Loss in MS-Like Disease. There's a mouse model of multiple sclerosis, in which myelin is inflamed. The drug is a nucleoside analog kamuvudine-9. Still early in research and not ready to be deployed, but promising.

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Oh crap. Amazon’s delivery driver smart glasses will reportedly take photos ‘almost constantly’ So these drivers will have to wear creepy video glasses. They don't look too fashionable. Someone needs to develop a blocker for this. 

Speaking of Amazon, they must have heard me: 
You want to learn AWS by building something. Then a thought interrupts: "What if I leave something running and wake up to a bill I can't afford?"
Yeah, been there, done that. It's so easy to let that happen. So maybe it'll be easier to get started with Amazon and learn their byzantine environment.

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One year after the end of the EV tax credit, is the future still electric? The best car is a hybrid car. Best of both worlds. Never understood the appeal of an all-electric car. It only made sense in the Bay Area, where there are charging stations everywhere.

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What happened? Nvidia program on pause year into deal with Oregon to get AI education in schools, colleges. I guess nVIDIA gave up on Oregon.

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Duh. Portland Housing Nonprofits Report Strain From Property Damage. This is how to run out of money. Of course, Portland needs to keep the homeless around, or else the non-profits will lose their business model. We need to reopen the state hospital and put these people there.
In recent years, some of Portland’s largest nonprofit providers of supportive housing have begun to face a remarkable new expense: They effectively had to start self-insuring their properties after insurance companies backed away amid surging costs to repair units that had been burned, flooded or left in disarray. 
What a waste of taxpayer money. 
Oregon providers warn shift from Housing First could push thousands into homelessness. No, the warning is it'll put the non-profits out of business. 

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30 September 2026

Holy crap! Anthropic IPO Prospectus Reveals $8 Billion Operating Loss. You'd think the company was swimming in cash, but no. Think it'll matter, though?

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Misleading AI-generated summaries can distort human memory. Turns out that when humans are presented with faulty AI summaries of meetings and such, they're more willing to say "Uh, OK..." rather than "Wait, that didn't happen!" This is scary, especially when AI is used to summarize clinic encounters. How often does your doctor correct errors, or just assume it happened that way? What about when Apple watches summarize recorded events. Humans have never had to face this before.

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Researchers at Google DeepMind have found a way to watermark AI-generated proteins without affecting their function. This is a way to track the provenance of their proteins. Paper here. Reminds me of Blade Runner 2029, where you can read the serial number of replicants. 

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Chinese publishers announced the creation of their new journal, Vita, which they aim to make as prestigious as western journals. To encourage westerners to submit, they are waiving the article publishing costs, for now. We'll see how this goes.

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The rumors are true: Reddit is sharply curtailing access to old.reddit.com and is killing RSS feed access as of November 13. All because of AI scraping and content bots. This will probably kill the allure of Reddit, and once again encourage alternate social media sites. We'll see. This would be an opportunity for Digg.com to come back, after their unsuccessful attempt at a comeback.

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OpenAI holds off on releasing new model over safety concerns, saying it "didn't quite meet the bar". I think frontier models are getting so advanced now that their should eliminate unrestricted release to the public.

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September 2026: the world today, as seen by one Polish guy. Excellent summary of the energy crisis that Poles face, and how it's interconnected with world politics. The country is in a tight spot, and they're relying on a lot of luck, since they haven't prepared for disaster, and are suffering from the decisions of the EU, of which they are a member. The visuals are superb.

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Oops. AI models keep posting screenshots showing sensitive data from inside tech companies. No wonder when their employees use frontier models to ask questions. I've wondered why stuff like this wasn't uncovered before.

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New Zealand teachers union demands that teachers not be replaced by AI. Coupled with my post yesterday, I would say they're arguing from a weak stance. Portland's teachers should take note.

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The latest release of Firefox has changed the browser's appearance. The working viewspace is more spacious and the corners are rounded. I've had to modify my userChrome.css to make things they way I like them. But so far, no major change in functionality.

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Seattle is set to adopt eye-popping minimum wage amid business exodus. Not to mention the millionaire tax.
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29 September 2026

Another favorable MacStudio M5 review, even with just 128 GB of unified memory. I think these will sell well, despite their price.

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Claude discovers a novel enzyme system with CRISPR-like repeats. Will there be another gene-editing system? Guess we'll just have to wait and see.

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People are creating virtual AI incarnations of deceased relatives. It's kinda creepy but understandable. They already did it for Salvador Dali. Why not others?

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AMD acquiring Fei-Fei Li’s World Labs AI firm in deal worth $8.2 billion. Wow, I'm surprised that World Labs is worth that much. But I think AND really purchased an AI firm, because they want to compete with nVIDIA. Congrats to Fei-Fei.

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Gene-edited bananas that don’t go brown could hit UK supermarkets. They used CRISPR-Cas9 to silence three genes that code for polyphenol oxidase, which causes the browning.

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Stephen Wolfram addresses the question: What’s the Future for Pure Math Research in the Age of AI? He's in a business where advanced AI might put him out of business, so he has skin in the game. Looks like he's still optimistic and is in favor to letting AI endeavors continue. Stephen is more of a practical math guy, and his essay spends a lot of time on whether it's worth devoting time to "useless" mathematics. I'm reminded of G.H. Hardy's quote that all good mathematics is useless - "the study of mathematics is, if an unprofitable, a perfectly harmless and innocent occupation."

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1 in 8 cancer cases worldwide is caused by infections. Yeah, physicians know about HPV, HIV, EBV, H. pylori, and even Clonorchiasis and Schistosoma haematobium. But 1 in 8 is a lot, and that's a concern. And so much of our genome (>50%) has been affected by transposons, it's not funny. It's amazing we don't get cancer more often. 

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Proof that puzzles can reverse cognitive impairment. It helps to keep the old squash active.

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This University of Chicago business school professor has authored 258 academic papers in 2026 (so far). Yeah, it looks like he uses AI a lot and fabricates his papers. There are many journals that have low standards and will publish all kinds of crap, as long as you pay publishing costs. They don't care.

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