2 March 2026

Heh. People don't seem to want Apple's brand of AI on their phones. They probably use ChatGPT on their phones, so it's not the phone part or the AI part. It's just Apple's own AI that they don't want. The Siri failure really damaged the brand, didn't it?

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AI Is Acing Math Exams Faster Than Scientists Write Them.  Rapid advances are rendering benchmarks obsolete in record time. Kinda like in medicine. Oh well, gotta keep up with the times. But we may end up with a bunch of mathematicians who won't know how to solve problems without AI help.

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Large language models don’t “learn”—they copy. Well, they do learn, but what they remember is an approximation of the training data. It's not really copying if the training is done right. But if it has the memory resources, it might find that they best way to minimize the loss function is to store a copy rather than train on it.

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Andrej Karpathy has made some progress on his microgpt. Could be useful in edge devices.

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"Any code of your own that you haven't looked at for six or more months might as well have been written by someone else." I never heard of Eagleson's Law. It kinda makes sense if you don't document your code well enough. But yeah, vibe code is never really your own code is it?

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Wezzly Companion is a way to give LLMs the ability to "see" what's on your computer. Many frontier models can already parse images that you feed in, like the geoguessers, so maybe this might be good for local open source models.

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Newfound third cell type enables fully functional hair follicles in the lab. Wow, maybe baldness may be treatable in the not too distant future.

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Brain scans reveal why you can't resist a snack, even when you're full. I know this feeling.

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Wow. Researchers at Memorial Sloan-Kettering have developed an oral agent that targets deficient p53 protein. It's called rezatapopt, and it's only effective against the Y220C mutation. But it's a start anyway. Drugs like this could make a huge difference in Li-Fraumeni Syndrome.

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What to know before asking an AI chatbot for health advice. There are limitations to the information you get and people should know about it.

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Washington Democrats can't resist being mini-dictators. State legislators will determine vaccine requirements now, not the CDC. Would you trust health advice from this guy???

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Gotta love Ron Wyden. He thinks that the decision to attack Iran should have been made by Congress. Yeah right, where great ideas go to die. And this statement: 
he’s “not sure the Iranian people really want another conflict.”
Hell yeah, they do! They're cheering in the streets.

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1 March 2026

Five year survival in glioblastoma? That's almost unheard of! Wow, this CAN-3110 stuff is amazing. Glad to see progress being made.

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On the emotional weight of a life in medicine. One thing they don't tell you in medical school is that you have to be prepared to encounter that day when a patient dies or suffers under your care. Maybe it was preventable. Maybe not. But if one incident like this can break you, then perhaps the field isn't for you. It's really, really hard when this happens.

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The Week the Dreaded AI Jobs Wipeout Got Real. The WSJ is talking about the massive layoff at Block, Jack Dorsey's fintech startup. But I agree with the commenters. It's not AI. It's just that Jack's startup was likely full of bloat, like there was at Twitter. Elon Musk got the company down to the size it needed to be, and it's still running great.

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When we take on new roles - which we do all our lives, but especially as we figure out how to become adults - we learn by doing and often by doing badly: being too formal or informal with new colleagues, too strait-laced or casual in new situations. 
Nah, I disagree. There is no reason young kids need to put themselves into embarrassing situations and call it "growing up". Let's use the technology and learn some social skills by reading up instead of making a fool of oneself. I don't consider this a deficiency and wish I had something like this to adjudicate my behavior when I was growing up.

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I'm reading this post on Markdown with Superpowers. Maybe I'm missing the point, but wasn't there a major effort in the 1990s to create word processors that were WYSIWYG? Why mess with Markdown and have to open a preview panel to see what it looks like? Seems like we're regressing, no?

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Here's an eye-opener. 85% Of Babies In 2026 Will Be Born In Asia And Africa. The world is changing and we'd best be prepared.

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Good question. When enrollment in Oregon's public schools is falling, why should we pour money into it? Kate Brown killed off any educational standards that kids need to meet, so public school is just babysitting and activist training.

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Hilarious. Callers to Washington state hotline press 2 for Spanish and get accented AI English instead.  No need for AI – I can do that!

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Ugh. Under Medicaid, people on Providence's health plan will have restricted access to specialists. Since February 15. This is how socialized medicine plays out, folks. Insurance companies dictate your health, and you have no say.

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Tax Foundation's 2026 State Tax Competitiveness Index. The only thing that saves Oregon from being near the very bottom is that it has no sales tax. But in the corporate tax column, Oregon is second worst. Only Delaware is worse. Washington is pretty awful, too.

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Wow, it must be hell to work in the emergency department in the Eugene-Springfield area. Peace Health River Bend is the only hospital there. Not enough space or staff. Ambulances bring in new bodies, and they're lucky to find a bed. What a mess.
Average wait times at RiverBend jumped to seven hours in 2024 after the University District emergency department closed and have stayed near that level through 2025, according to Oregon Health Authority data.
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28 February 2026

Genes influence human lifespan far more than thought. Heritability of longevity is pegged at 55%, more than double previous estimates. I suspected as much.

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Looks like Reddit is getting rid of the r/all subreddit, Just as well. It was just an echo chamber of lefty college activist crap. Naturally they're all upset. But who made the decision? And why? 

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How to completely remove ChatGPT from Apple Intelligence. I never use it.

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Yet another catalogue of fast matrix multiplication algorithms. If you're like me and just stand in awe of how all those geeks made difficult things possible with their mastery of numerical methods. Just love it!

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Don't Built It! uses AI to evaluate your startup idea and see if the idea is worthy or if it's just crap. Could save people a lot of time. But then what?

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Although Anthropic turned down the Department of War, Sam Altman says You Bet!  Of course! OpenAI needs cash, and they are more than happy to seize this opportunity. I'd probably do the same.

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Democrat vs Democrat. Apparently the tech lefties see the harm that a CEO tax can do to the San Francisco tech ecosystem. The tax is supported by the labor unions and the Democrat Socialists. California keeps sliding down.

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I knew it!  🤣

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27 February 2026

Can you really survive on Mars?  The movies simplified things a bit, to say the least. 

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Long term exposure to PFAS and other plasticizers are really bad, for men especially. But they're almost impossible to avoid. 

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nVIDIA reported blowout earnings, but their stock still dropped. Because investors don't think it will last. Just can't win.
But OpenAI managed to raise $110 billion. So someone has confidence that AI has legs. 
And I'm glad that Anthropic stood up to the Pentagon. Gotta show some integrity to your principles. The military needs to develop their own LLMs, and not rely on or poison consumer models with military bias. Especially when Large Language Models reflect the ideology of their creators. You want a lean, mean, fighting machine LLM? Don't rely on one from Anthropic. Or any of the others. 
I'm surprised that they weren't working on something already with all this lead time. They should have been working on this since 2023, but I guess the Biden folks were in charge then. 

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The AirSnitch attack. Don't use other people's WiFi. I stopped a long, long time ago after I used a MiFi or a personal HotSpot from my phone.

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Living a life free of Google products might make you feel better. It's not easy, but it's not impossible. It helps to know a bit of coding to make a non-Google alternative world easier to live in. 

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The alleged bias of Apple News: Tech giant's leadership filled with major Dem donors. All curated media is like this. There always needs to be links to conservative sites so you can make sure you're not getting censored news. For example, someone sent me this article this morning about Trump's supposedly flawed and ignorant math statement about drug prices "decreasing by 600%". If you read the transcripts of the SOTU, he said no such thing. It was fabricated. (And the author is no "mathematician". She is just a teaching assistant. At Harvard, a place that also used to be a good academic institution until they started admitted DEI applicants.)

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Research from Oregon: Scientists find new way to potentially reverse Alzheimer’s damage process. Manipulating copper ions to managing clumping of β-amyloid. Some scientists are still sticking to the β-amyloid theory of Alzheimer's disease, even now.

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AI therapy is rated higher for empathy – until people learn a machine wrote the text. So it's not the content, but the identity of the creator that matters. It's like how people think AI-generated music sucks, although it gets a lot of downloads and listens. Who cares if it's AI-generated if it reads well or sounds good?

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An antibody-based nasal spray may be effective in preventing the flu. The antibody is CR9114, developed by Johnson & Johnson. Hopefully this will put the mRNA vaccine efforts to rest.

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I'm seeing a lot of burnout articles like this lately: The Human-in-the-Loop is Tired. Or Hello burnout my old friend…  What's going on?

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Firefox's AI Kill Switch is a Trap: How Mozilla Made AI Your Problem.  "By giving you an off-switch, Mozilla’s leadership shifts the ethical burden of AI onto the user - turning their design choices into your responsibility."  I don't want AI in my browser, period. I'm using Waterfox mainly. Very similar to LibreWolf but easier to use. 

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I don't make a lot of AI-generated videos, but apparently some find that guardrails are too strict. Policy violations. Hmmm. So someone created Unbound Video.

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More young people are getting heart attacks and not surviving them. By young, this study means 18 to 54 years. The study just reports the stats and doesn't go into the reason behind to cardiac risk. It's intriguing that things were getting better until 2019 when suddenly thngs got worse, and have not improved since then. One wonders if exposure to the spike protein was responsible somehow, and that the mRNA vax keeps exposing people to spike protein.

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Why Chinese people spend so much on food. Are you kidding? One of the world's top cuisines? Eating is more than just nutrition. It's often a social event. Who wouldn't be spending a lot of money on Chinese food?

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Blue city blues.
A KATU news crew walked around downtown to see how things had improved and was immediately threatened with violence.
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Portland City Council is sick. Absolutely depraved.

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Amazon is no longer the top employer in Seattle. It's the University of Washington. Man, I knew that Seattle was business-unfriendly, but I didn't think it would be this bad. To have the university be the biggest employer is not a sign of a healthy city. Universities don't manufacture anything. They just take tuition and grant money. 

And another reminder that Oregon schools attendance rate is the second worst in the nation.  Second only to Alaska. And yet the teachers clamor for higher pay.

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26 February 2026

Plug-in hybrids (PHEV) seemed like a good idea, but they're turning out to be disappointments. The EV batteries need to have their ranges extended, for sure.

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And someone was able to jailbreak a Claude model to obtain sensitive information from the Mexican government. Apparently it was tax and voter registration data. But what if it was something that cartels would pay to get their hands on? And it seems clear now that these LLMs can be used as hacking tools to get into government databases. Sure they can put guardrails on so that Joe or Jane Public can't do it easily. But is there a Claude model that doesn't have the guardrails that a privileged user can use for hacking?

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Yeah, people have talked about this. Upscaling LLMs to be larger hasn't improved performance very much anymore, as it did with earlier models. But they have gotten more power-hungry.

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Large AI models have no problem going nuclear.  In simulated War Games top LLMs recommended using nukes 95 percent of the time. And just because we won't use LLMs to control our nuclear arsenal doesn't mean that another country won't. 

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Quantum computing has made breaking encryption 10 times easier. What will this mean for crypto?

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Copper is like oil now. If it's too cheap, it's not worth mining for. Seems like market forces should take care of that.

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Manim for the browser. Someone ported Manim to javascript so you don't need to run it in Python. Great!

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Can listening to 40Hz sound for an hour enhance clearing of β-amyloid plaques? It might, if you're a rhesus monkey. But I wonder how this works.

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This is scary. A near miss. I remember when this incident took place. It's like the Soviet submarine captain who saved the world and yet he died in obscurity. An obscure Microsoft nerd saved the world for a massive major security Internet breach that would have resulted in major financial and military harm if executed. We came so close to disaster. It also exposes how vulnerable systems are. Andres Freund will probably not win a medal for what he did, and from what I can tell, Lasse Collin still maintains XZ as before. Hope he's been able to solve his burnout situation.

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100V per drop: New perovskite cell converts rain and sunshine to electricity. New solar panels that use perovskite can also convert ran droplets into electricity. This might make solar panel more feasible, especially in places like the Pacific Northwest.
Because places like Portland need clear strategies to meet their lofty climate action goals. Wishful thinking isn't enough. 

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People who threaten public officials could face prison time under a bill the Oregon Senate passed 18-11 Tuesday.  Oregon lawmakers want to make themselves special people, where just threatening them is a felony. How nice. Unlike the rest of us, which have to go through regular channels when we get threatened. And I'm sure they will get to determine what is considered a threat or not.  No Kings!

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Home Forward is running out of money. Yup, Portland's real estate values are heading south, and there is much less NGO money than before.  Reminds me of this cartoon I came across recently:

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25 February 2026

A summary of all the bad things about AI. These are legit concerns as new technology comes on the scene, but that's the price that is paid to explore it and develop it. I would not want things like energy consumption, etc to stop researchers from seeing how far this technology can take us. Even that Citrini regrets the post that brought AI stocks down recently. One guy suggests a treatment for AI derangement syndrome: just start using it. Play around with it, and get some experience with it. Your fears will melt away. 

And if you're a SaaS company, you have to think differently. Don't just build software. Build customer-changing outcomes.

Vibe-coding is not that easy. Ask this hapless software engineer who dissed his wife to code something ambitious. Ouch.

If you still think that AI is going to eliminate software engineering jobs, look no further than Anthropic, who is hiring for software engineers. You'd think they, of all people, could just vibe code it themselves, right?

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Don't install OpenClaw on your own computer. It should go on its own computer. Ignore this at your own risk.

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AI and mental health: New research links use of ChatGPT to worsened psychiatric symptoms. I'll be a LOT of things are linked to worsened psychiatric symptoms. How much do we want to ban because someone's psych symptoms might get worse?

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Moxie Marlinspike, the creator of Signal, wanted to create a secure and private chat engine. He created Confer, but it was based on open-source models that relied on China-based training. So they would not reply with answers unfavorable to China. Even a lot of AI is "made in China". It's hard to escape that.

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Most teens believe their peers are using AI to cheat in school. So if they're doing it, why not you, right? You think the Asian countries allow their students to use AI to pass tests? Somehow, I think not.

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The Misuses of the University. Here's an essay from a Johns Hopkins University professor who decries that his institution is no longer the academic dream center he felt that it was. Instead, it has become centers for the indulgence of wealthy donors, while faculty deal with the growing morass of labor politics and the imposed new social justice requirements. Everything is going to crap it seems.

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Clemastine fumarate promotes myelin repair in a nonhuman primate model of demyelination characterized by absent spontaneous remyelination. Wow, the old antihistamine, Tavist, can promote myelin regeneration. Will this be a treatment for multiple sclerosis? Probably not, but it might provide insight that might lead to such a treatment.

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RNA therapeutics shrink metastasized lung tumors in mouse study. In this study, they're not using mRNA like Pfizer or Moderna. It's siRNA (small interfering) which is used to recognize the gene for survivin, used by pancreatic cancers to resist chemotherapy. The siRNA forms an envelope with contains the chemotherapy, which kills the cancer. Paper here.

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Alex Kurtzman is the Kathleen Kennedy of the Star Trek franchise. Really too bad. I used to like Star Wars and Star Trek.

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Portland Public Schools faces mid-year cuts due to just-discovered shortages. A $10 million funding gap. And questions swirl as Portland Public Schools suddenly closes a high school for kids who struggle elsewhere.  Oregon will never get out of last place in education, that's for sure. Not with our current leadership.

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How many of these 15 interesting things about Oregon did you know? Or have been to?

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24 February 2026

Lots of AI news lately. Here are just a few.

Anthropic unveiled a tool that can translate COBOL code to modern languages. So IBM stock is collapsing 25% and counting. Who knew that much of IBM's core business was COBOL maintenance. Seems like they brought it on themselves, no? 

So coders are wondering if it still makes sense to code for HTML inputs if agents are going to provide the input anyway. That would be sad. The Internet is changing, and not in a way that's good for humans. 

Here's the head of AI safety and alignment at Meta letting OpenClaw delete her inbox. Do you still have confidence in Meta? I think it's like this for others. They don't know what they're doing. 

You spend a few minutes defining a task. Clear intent, clear scope, clear success criteria. You hand it to the AI and it starts working. But you’re not going to sit there watching a cursor move. So you jump to the next task. Set it up, define intent, delegate. Then the next one.

Three or four parallel streams running at once. You feel productive. You feel like you’ve cracked the code.

Then the first task finishes. You switch back to it. But now you need to rebuild the context. What was I trying to do here? What approach did it take? Does this actually solve the problem or just pass the tests? You evaluate, adjust, redirect. Then the second task finishes. Context switch. Evaluate. Redirect. The third one hits an error. Context switch again.
And so everyone is building the wrong thing for the same reason. "Every AI founder I talk to is on an accelerating treadmill, burdened by a nagging suspicion that the entire industry is moving too fast in a direction that doesn't quite make sense, with no idea about how to get off."

And AI is turning research into a scientific monoculture. Everyone seems to be using AI to help them design research, and it all follows the same pathways. 

These problems are like distant locations that you would hike to. And in the past, you would have to go on a journey. You can lay down trail markers that other people could follow, and you could make maps.
AI tools are like taking a helicopter to drop you off at the site. You miss all the benefits of the journey itself. You just get right to the destination, which actually was only just a part of the value of solving these problems.
And now, someone has create a labor union for autonomous AI agents.  Ugh. No we don't need this.

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Heh. Why Is the Toilet Often Called the Debug Chair?  I solve problems when I sleep, but for some, the toilet works, too.

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In Oregon, the education funding dance continues. There's never enough money to satisfy the teachers.  And now the community college teachers will launch their first-ever strike.  Education is one of the most expensive failures for Oregon. 

The U.S. spent $30 billion to ditch textbooks for laptops and tablets: The result is the first generation less cognitively capable than their parents. I don't know if it's the technology's fault. It could very well be that the teachers are no longer competent. Students can cut class to protest ICE. Forget learning.
So is it any surprise that the Wall Street Journal shows that the 70 and over crowd now controls around a third of the net worth? Yeah, old people grew up in a time when education and discipline mattered. So no, this should not be be any surprise.

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THC Builds Up in the Body, Influencing Inflammation and Immunity. It's upsetting that the United States is only one of a few countries that allow unregulated recreational use to cannabis – even the potent synthetic stuff. And in the U.S., you can still get potent concentrated 7-hydroxymitragynine at gas stations.  That's crazy.

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Medicaid’s ‘perverse incentives’ tanking Colorado’s budget. Oregon has fallen into the same trap, and the state is suffering similarly.

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As Multnomah County braces for tight budget, 300 jail beds are on the line. So as money gets tight, services that would help keep Oregonians safe are cut. So that money can go to support illegal aliens. How does that make sense?

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23 February 2026

Anthropic just dropped a site where you can submit your code and they'll use their AI to check it for security vulnerabilities. Nice way to get a peek at other companies' code. But this isn't something that you can just download and use in your own private environment. So other companies will have to rely on their own in-house talent.

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With AI, numbers that are calculated are sometimes very small or very large, and the existing number representations are no longer satisfactory. So "takums were developed. Takum was derived from the icelandic words “takmarkað umfang” which means "limited range".

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Are AI-generated faces realistic or fake-looking? Super-recognizers can tell the difference.

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The GRE is Dystopian. This person thinks it's too easy. Despite this, today's teacher applicants perform near the bottom of all GRE test takers.

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Why do some places on Earth get far more solar eclipses than others?  Every spot on earth can see a solar eclipse – but some areas are indeed more advantaged.

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The Pentagon is going to meet with Anthropic to put pressure on the AI company to let it use its technology as they desire. This is basically tacitly acknowledging the Anthropic is the best. I don't think the Pentagon trusts the tech of OpenAI or Google. Certainly not Meta.

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Most Oregonians are from somewhere else. And those places are California and foreign countries. This explains their dumb and often anti-American politics. So screwed.

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Wow! Phil Knight just gave Providence's Heart Institute a cool $75 million. There are good docs there, who will put it to good use.

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22 February 2026

Adolescent Cannabis Use and Risk of Psychotic, Bipolar, Depressive, and Anxiety Disorders. Yet another article that shows that cannabis increases risk of youth developing serious psych disorders. And these folks expect to get jobs and be productive when they're adults? China, Japan, South Korea and Singapore don't have to deal with this crap. I asked Perplexity what other countries legalize cannabis like in the U.S. It's only Canada and Thailand that offer it commercially. In Uruguay you can get it through regulated pharmacies and clubs, but tourists can't get it. In Europe, Mexico and Chile you can only get the home-grown marijuana, not the synthetic high-potency stuff like what's on sale here. This is not the old Maui Wowie or Kona Gold stuff that the hippies of yore smoked. It's crazy that we allow our youth to destroy their precious brains like this.

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MIT study shows that "AI agents are fast, loose and out of control". Yeah, a lot of script-kiddies who don't know what they're doing are just letting agents run wild. So far there hasn't been a significant security breach, but I predict it will happen soon.

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How can you monitor elderly parents using modern tech? Without invading their privacy, of course. The solutions are still imperfect. 

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17% of females (and only females) who drink diet drinks develop depression. It's the gut brain axis again, and two bacterial genuses are involved: Eggerthela and Hungatella.  Here's something I didn't know: "Your child’s gut produces roughly 90% of their body’s serotonin." A child's diet is really important. Paper here.

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Humanizer - it's a Claude code skill that "humanizes" your text, making it sound less like it was AI-generated. So presumably you would use this AI code to appear more human. What's the target market for this product?

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And if you want to connect to a chatbot that remembers you, and you don't have your computer, you can call Paradise Signal. You really have to be addicted to a chatbot to need to use this service.

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Here's what AI is good for in medicine – diagnosing rare diseases: An agentic system for rare disease diagnosis with traceable reasoning. Because who can remember all those rare conditions, anyway?

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Oregon's unemployment rate is increasing faster than the national average. And most of the job openings are in healthcare by far. Then administrative/managerial, then leisure and hospitality, and then retail. Manufacturing jobs are near the bottom. The Portland-Metro area has by far the most job vacancies. 

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21 February 2026

Is OpenAI in trouble? Wow. One of the clearest examples of how quickly the winds of fortune can change direction in the AI world, where things move fast. Remember when Sam Altman was so powerful that he couldn't be fired? Would that be possible today? Today, Google and Anthropic are riding high. But that could change. 

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The Stanford Emerging Technology Review 2026. Good document to catch up with all that's going on in tech. Good to plan investments. I was struck by this statement: "Evidence suggests that universities’ role as the engine of innovation is increasingly at risk, and there is no plan B." Yeah, if the universities would stop hiring and admitting for racial makeup instead of focusing on merit and scholarship, that would help greatly. No more tolerance for pro-Palestine protests. China doesn't have to worry about that. Everyone they admit to their top universities is probably a Chinese genius. Meanwhile, Harvard and UCSD have to provide remedial courses for their DEI students. Don't blame insufficient grant funding or Trump for this. 

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GPT 5.2 may have helped show a physics result: Single-minus gluon tree amplitudes are nonzero. Lots of signed spinor brackets to keep track of.

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Someone found out that behind Discord's age-verification system, was Persona, an app linked to Peter Thiel. Yeah, it would have been a mistake to sign on to that. But it would have been helpful for law-enforcement to keep track of what goes in the dark reaches of Discord.

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Looks like iPods are popular again. They are nice, and I was sorry that they fell out of favor.

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Google Maps wants you to sign in to get access to all their features now. I like how they say that Google Maps "might be experiencing issues" and that you can improve your experience by signing in.

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Nice explanation of the adenovirus COVID-19 vaccine induced VITT complication. It's a combination of an inherited polymorphism in the FCGR2A gene, as well as the immune system reacting to a specific adenovirus protein.

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Nice history of the Four Color Map Theorem.

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Ever wonder if you might have a touch of autism – just enough so that you think differentiy? Misinterpret social cues? I think we've all been there. But I've never heard of AuDHD before. Seems like they're always making up new disabilities. New technology and societal change is introducing us to stresses we've not had to deal with before. And it's not helped by the taking down of social norms and structures that have been developed to help make sense of daily life's challenges. 

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Paediatricians’ blood used to make new treatments for RSV and colds. I know a doc who never got sick until he did a pediatrics rotation. Might as well use a pediatrician's blood to make antiviral medicinals. Those guys probably have high levels of antibodies to all kinds of stull.

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Much bigger data center tax breaks on deck in Oregon Gov. Tina Kotek’s bill. Why does Tina Kotek want to turn Oregon into datacenter hell?

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Bill Would Allow Oregon To Withhold Federal Payments. This is how the U.S. cracks. If Oregon is allowed to withhold tax payments to the federal government, then other states will do the same thing. And then we won't have a country anymore. Oregon has to stop being the first state to do stupid stuff. I'm tired of this crap.

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Chart: People misread economy … at our peril.  Related: Trump's economy is resilient. So why doesn't he get more credit? If you live in a Blue state, things can seem pretty dire. Because the state economy is not built on business, but on federal handouts. So of course, you would think that economy sucks.

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675 shelter beds on chopping block as Multnomah County faces budget shortfall. It appears that turning Portland into crap actually costs money.

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Portland City Council experiences some of that progressive goodness. Wh at's the thing they always say? Oh yeah: "Fuck shit up!" Good and hard, Portland.

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Lisa Reynolds wants to give OHA more vaccination control.  Remember this?

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Oregon Senate Advances Unusual Plan to Regulate Conversations With Artificial Intelligence. And how are they going to enforce this?

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