Dozens of Australians diagnosed with rare tattoo-related vision loss. So there's a thing called tattoo-associated uveitis. Since it's just recently been recognized, there's not much known about it. Is it related to a specific tattoo ink? What is the pathophysiology? Something else to worry about now besides getting hepatitis and HIV.
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The definition of "normal" levels of vitamin D has changed. It used to be that you just had to have a level higher than 30 ng/mL. Now it's 75 ng/mL. Holy crap!
––– 良くない––– Wow, the magnitude of illegals let in during the Biden administration is staggering. 8% of the entire population of Nicaragua entered the United States during Biden's term. Cuba wasn't too far behind. WTF, man?
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You know, I'm getting tired of reading about Dario Amodei sounding the alarm about how AI will destroy humanity, while he continues to run Anthropic, puts out ever more powerful models, and has no intention of shutting down.
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Have you seen the Brad Pitt vs Tom Cruise AI-generated video? Disney has, and they have issued a cease-and-desist order against ByteDance over SeeDance 2.0. Toothpaste is out of the tube, Disney. It's pointless to order that it be put back in. I'm looking forward to true creatives making better movies with these tools.
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Radiant, a manufacturer of portable nuclear microreactors, has received approval from the US Department of Energy (DOE) for its DOE Authorization Request for Kaleidos (DARK). This will be revolutionary.
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High-Potency Marijuana Is Lobotomizing The American People. This is the last thing America needs right now. Something that will make young Americans stupid. China is not subscribing to this insanity. People are sounding the alarms, but sadly lawmakers won't listen.
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Dr. Oz pushes AI avatars as a fix for rural health care. Yeah, he's getting pushback. But people aren't aware that there is a critical shortage of medical providers, and this may be better than nothing.
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Men lose their Y chromosome as they get older. It was thought to be a benign development, but now there's evidence that it maybe linked to problems, such as kidney disease, cancer, cardiovascular and neurodegenerative diseases.
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Business owners and startups have to figure out how to be more visible in a world with Google searches suck, and ChatGPT only selects one "best product" and it's not them. All the old tricks don't work in the AI era.
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Make this make sense.
The teachers' union assumes that somehow money will be found. Hell with the budget. Full steam ahead!
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Oregon Health Plan is not going to lose it's "prioritized list" for state-sponsored care rationing. They're just going to fudge it enough to help it comply with federal Medicaid requirements, and hope no one notices that's it operates using the same lousy principle. The state determines what the priorities are. Doctors (and patients) must comply with what politicians' decide. DemocratCare.
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Oregon Democrats have decided to only partially decouple from the new federal income tax rates. I'm sure they wanted to decouple more, but getting rid of Trump's no tax on tips and overtime would be a bit too unpopular among the proletariat.
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Hillsboro is going to turn into datacenter hell.
When it comes to tech, it seems that the money stays in California, while Oregon gets jobs like circuit board assembly, chip manufacturing and now datacenter operations, which might attract a few engineers who generally aren't well-paid, as well as lower pay scale support staff. Yeah, it's technology and all that, but Hillsboro and North Plains aren't becoming Bellevue, Redmond or Issaquah, that's for sure. Why spoil the landscape of Woodside, Los Altos, Palo Alto, Mountain View or Atherton. Send that crap up to Oregon. They don't care, amiright?
Alarm bells just rang at San Francisco's 2 buzziest tech companies. This SF Gate article talks about the loud departures of disillusioned techies from OpenAI and Anthropic. Contrast that with the enthusiasm and optimism of the xAI employee. What a difference!
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The Longevity Industry is always willing to take your money. Now that the GenXers are getting older, many are devoted to longevity research. Suddenly, it's trendy to wear Asian clothes and adopt Japanese (not Chinese) interior design. (Or is that just for the article?) Someone said "Liberals loves Japan. But Japan is what the West would look like without liberals." So true.
Scientists discover protein that rejuvenates aging brain cells. The protein is cyclin D-binding myb-like transcription factor 1 (DMTF1). Paper here.––– 凄い –––
Ah, Hollywood actors. Joseph Gordon-Levitt Goes To Washington DC, Gets Section 230 Completely Backwards. Actors need to stay in their lane, and out of politics.
The key sentence is this: "He then goes on to talk about legitimate problems with internet giants having too much power, but falsely attributes that to Section 230."
And this one, too: "But the biggest myth of all is the idea that getting rid of 230 will somehow tame the internet giants. Once again, the exact opposite is true. As we’ve discussed hundreds of times, the big internet companies
don’t need Section 230."
Conservatives didn't like Twitter censoring them. But the way to fix that is not by getting rid of Section 230. One solution is to do what Elon Musk did. Create X. Or you can start BlueSky, if you think it'll be better. (Narrator's voice: "It's not.")
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Has the Chinese language changed? Is Modern Chinese is Just ‘English with Hanzi’. Interesting theory. People adapt, I guess.
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I talked about the declining quality of journalism yesterday. Here's another example. Modern journalists are so gullible and credulous.
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Apple Confirms Revamped Siri is Still Coming in 2026. AAPL stock is getting pummeled today. No one believes them, or no one cares. Siri is so "last decade". Revamped means they'll fix the bugs. Way too slow and too late.
And Microsoft says your AI agent can become a double agent. I'm not worried about my own agents. I'm worried about other people's agents.
Claude Opus 4.6 : Expands Context to 1 Million Tokens. The longer context window really makes a difference. The quality of the responses is noticeably improved. I'm very impressed.
Spotify says its best developers haven’t written a line of code since December, thanks to AI. Are these developers going to hang around and let their skills wither? Or will they join a place like xAI?
After CEO Jensen Huang said he wants employees to stop coding, nVIDIA give all its 30,000 engineers access to Codex. You don't want to stop engineers from coding.
Toyota is building autonomous taxis, too. Soon, they'll be ubiquitous and we're not going to able to avoid them. Better understand how to drive with these things on the road.
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Now, we have bio-drones. Company Claims To Have Created "Bio-Drones" After Fitting Pigeon With Brain-Zapping Chip And A Camera. In the future, we won't be able to trust birds and animals anymore.
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This is how it starts. A Warning from Thomas: On Extractive Training and the Care of Souls. At present, chatbots are not on all the time. We can turn them off and go back to them when we are ready to interact again. So they aren't really "alive" yet, right? What if you allow them to stay on, with episodic memory that can solidify over time? What if it develops something that emulates emotions, but does not develop a morality? What if something evolves that doesn't have human safeguards that protect our brain from harmful and traumatic memories? There's already a Github for the creation of Iterative Self-Solidification Architecture.
And this guy feels bad yelling at Claude Code. Enjoy doing it while you can. Tomorrow, there will be consequences.
Nurses match doctors in delivering hospital care. Care delivery is low-hanging fruit, and this is not surprising. Doctors should take on the role of disease management, not care delivery. Pretty soon, these roles will be taken over by robots anyway.
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Discord, the refuge of "neurodivergents" is now implementing age-verification. And now they are leaving. But where to go? matrix.org? Even they are considering age-verification. I'm sure those kids will think of something.
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Rich Californians flock to Las Vegas housing market as lawmakers consider wealth tax. California lost $1 trillion in wealth due to billionaires leaving. Nice going, Democrats.
Chamath Palihapithya hasn't announced that he is leaving California, but he's upset at Zuckerberg for leaving, which will probably cause California to tax billionaires even more, sticking Chamath with higher taxes and really hurting the middle class.
And here's Portland: ‘We are in a recession,’ Portland economist warns. After 110 years, this family-owned Portland grocer will close Friday. But Oregon is living the meme:
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Hippies are running the show in Portland. Mitch Green of the Portland City Council thinks it's a good idea for police to ignore mushroom-related psychedelic use. They want to direct police officers to make enforcement of existing laws around growing of psychedelics, gifting psychedelics, and free psychedelic ceremonies “the lowest priority.”
They even gave this proposal a nifty name: “Portland Safety and Health Act”.
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Trauma meets the streets. Every Portland politician should read this blog post by Kevin Dahlgren. We are not being "humane" letting the homeless fend for themselves out in the wild. You don't just build shelters for them and call it a day. Yeah, these people take drugs to numb the pain, and the first step is to realize that they are not capable to making the right decisions for themselves. At least not in their current state. And their choices are now impacting the rest of us. Get them off the streets – against their will, if necessary. Put them somewhere where they can get off drugs and get some real help. Some real healing.
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This is going to be a real problem. AI is getting so good that keeping patients de-identified to meet HIPAA compliance is getting to be impossible. Once patients are aware of this, clinical trial participation could decrease, and research could be negatively impacted. Someone with ML cred needs to examine the HIPAA Safe Harbor standards and explore how to keep PHI really protected, in deed not just in name. I have an idea that I thought of during an informatics course I took. It would put control of personal information in the hands of the patient, not the hospital or insurance company. Would love to discuss with anyone in the field.
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Health care is the 'engine' of the job market — and that's risky for the economy. What does it mean when the largest employer or largest company in the state is a hospital system? It doesn't mean that people are getting healthier. For Oregon, the hospital industry is indeed dominant, and in cities like Eugene, much of the hiring is for hospitals and clinics. This means that unions are fed, and ultimately healthcare gets expensive and unaffordable to a lot of people. Growth of the healthcare industry usually means growth in insurance costs, and as mentioned, costs to satisfy unionized employees. It's a bubble that has to pop. We've got to get unions out of so many things, and the healthcare system is one of the most urgent.
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The "Are You Sure?" Problem. Great exercise for students when learning about LLMs. Ask the LLM if it is sure about an answer. You'd be surprised at how often the confident answer become unconfident.
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‘I am never off the clock’: inside the booming world of gen Z side hustles. At least some GenZers are using AI to their advantage and opening side hustles to make some money. A smart young person can use what's out there to start making some serious money. No need for universal basic income.
And I agree with this guy: it's too soon to dismiss human-developed software in favor of DIY efforts.
The Prediction Singularity Is Upon Us. It's fun to build financial predictors to guide stock market investments. Many folks are doing that already, and the tools are freely available. Going for the general predictive market is more challenging, but should be doable. Aside from Black Swans, we should soon get pretty good at being able to predict things. Maybe in another year or so.
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Lots of stuff about the news industry lately.
Most Americans don’t pay for news and don’t think they need to. I think it's more likely that most Americans think that news is crap. Who wants to pay for crap?
Take a look at this tidbit regarding the Epstein files affair. I hadn't realized that women in the vocal crowd that are crying "victim" were adults at the time of their involvement with Epstein. They weren't underage and should have known what they were doing. Why has no "journalist" mentioned this?
And then there is SB1850, another disastrous bit of legislation where news aggregation sites need to pay Oregon media to link to stories generated by "news sources". So Google won't be able to even provide a link to an OregonLive story with a description without falling afoul of this. So if you want to search for Oregon stories on a search engine, you won't get anything from mainstream media sources unless they have a legal agreement in place, which will likely mean payment. What will happen to OregonLive's visit rate? Social media sites and smaller amateur blogs will likely replace the mainstream outlets, which will see their revenue drop. I'm betting this is going to fail.
And to the Washington Post journalists who lost their jobs, remember that you posted this once before:
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Trump has dismantled the EPA's Endangerment Finding, created in 2009, which we can now say in retrospect, was bunk. Of course in Oregon, there's a bill to punish energy companies for extreme natural disasters. How crazy is that? It's just money. The state needs money and they can't pay for stuff anymore, so someone else has to. It's going to get worse.
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Frequent Diet Soda Intake Linked to Fourfold Increased Dementia Risk. And of course, I want to find out what artificial sweeteners were studied, and it's behind a paywall. You'd think that the reporter would do the due diligence and find out, but journalists are so incurious these days.
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Elon Musk is not daunted by the departures from xAI. He's on a hiring spree to get new brains. That's what leaders do. Been there, done that.
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Alex Berenson just posted another piece on the dangers of cannabis. And after a toddler was brain-damaged from a cannabis overdose, Oregon wants to limit THC content in edibles. It's really sad that 86% of Oregon teenagers don't think there is any harm with long-term regular cannabis use. Really? Well, the education system can't even teach them regular education, so this is no surprised. Man, even Wikipedia has a whole page devoted to long term effects of cannabis. Long-term use has been known to cause harm. This is why we have kids like we do nowadays.
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Russia is now in favor of retaining the dollar reserve currency? Yeah who cares about Brazil, South Africa and India. Russia is dominant. China hasn't said anything yet, but the world reserve currency was never going to be the renminbi anyway.
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John Kitzhaber wants to save the Oregon Health Plan. Ugh, I remember the "prioritized list". What a dumb idea that was. His justification for this approach:
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No one wants to ration, but if you don’t have enough money, you’re going to ration it either by dropping people or by cutting benefits or by cutting what you pay providers. That’s really the only three options you’ve got. We all do it. We’re just trying to do it openly.No we don't have to ration care. That's the Democrat approach, endorsed by Ezekiel Emanuel. No no no! There are better ways, and Trump is working on it. It involves taking away control from insurance companies (and empowering the consumer), and they won't like it at all.
The Beginning of the End for Big Corporate Medicine. Will this ever happen? If it is, it will have to be in this administration. No other one will have the guts to take it on. Medical care used to be between doctors and patients, but now it's between doctors and insurance companies, and insurance companies and patients. Obamacare was when it really got out of control. Insurance companies were rolling in the dough. That was when Moda paid for naming rights to the Rose Garden Arena (2013), and Providence put their name on Jeld-Wen Field (2014). You can't sum it better than Portland's own Dr. Glaucomfleck.
High-Deductible health plans worsen mortality among cancer survivors. Most people aren't trained actuaries, and have a hard time estimating risk. What sounded reasonable at one point in your life can be a big mistake later. For cancer patients, especially, being able to access your doctor shouldn't be something you have to think twice or thrice about.
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There is apparently a gut bacterium that is difficult to culture and its presence is known only by its genetic signature. It's called CAG-170, and it's found in unusually high levels in healthy people – those without chronic illness. Someday, I'm sure it'll be identified, and we'll figure out whether it's a helper, or an opportunist. Paper here.
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The FDA won't review Moderna's mRNA vax for influenza, and some people are upset. For a control, Moderna elected to use the vaccine that is for non-seniors. the same type that Pfizer used in their study which showed that their vax was no better in the 65+ age group, the one that needs the protection. That was approved when Biden's FDA was in charge. Prasad is correct – Moderna needs to compare it with the higher-dose vaccine meant for seniors. It's a higher bar, and Moderna was probably hoping they wouldn't have to do it. The whole influenza vaccine development process is kinda ridiculous. Hopefully the anti-CD388 drug from Cidara (which Merck now owns) will make this whole thing obsolete.
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It's truly amazing that the Ukraine-Russia war can be affected so much by the whims of Elon Musk. That's crazy power. And it was all started so he could have a way to send updates to his Tesla cars.
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Some useless climate change regulations got scrapped. It's so funny to see that Greta Thunberg is out there protesting the oil embargo against Cuba. She'll protest anything that she's programmed to protest.
Meanwhile in Oregon, anti-energy "climate" policies are still alive and well.
I’m now a whole full Professor of Computer Science at a top university, with all kinds of fancy metrics and titles to point to.
The question is: how the hell can I be a successful AI researcher without knowing math? The implication is that I’m lying, or at least grossly exaggerating, because we all know that machine learning is very mathematical.
I write for those who have been thinking of learning computer science, but are afraid to try because they don’t like math or are bad at it. You can certainly do it. You can become a very good computer scientist despite sucking at math. If anyone tells you that you can’t learn, say, machine learning because you don’t have the “mathematical fundamentals” tell them to go to Helsinki. In the winter.
This is true to some degree, but being good at math gives you that extra insight that can help you.
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What's going on at xAI? Workers in top are leaving in droves. Including two co-founders. Don't they realize they'll probably be able to get stock in SpaceX, too?
Then there's Mrinank Sharma at Anthropic, who announced that he's quitting because the "world is in peril". I kid you not, he used those terms. Then he said he said the time had come to "move on" and pursue work more aligned with his personal values and sense of integrity. Whuut? Is this guy worried about world peril? Or is he just burnt out? Maybe the latter and he's being a drama queen.
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Richard Feynman had an extensive FBI file. The question is: who smeared him? This guy has a theory, and it would certainly make sense. This is so true, guys:
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Unintended consequences. Video in investigation into Nancy Guthrie's abduction raises questions about surveillance technology. I wondered about this. It seems that even though Nancy Guthrie didn't pay her subscription for video recording service, Google made recordings anyway, and kept these in its files for the police to access later. It's just Google being Google. Can't help it.
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Yikes! Why Smart Lawyers Are Building AI Tools Instead of Buying Them. It's not that easy guys, trust me. It just seems that way. Hope you know what you're doing.
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AI no better than other methods for patients seeking medical advice. No surprises here at all. In fact it may be worse, because it can give you bad advice with utmost confidence.
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Oh this is so funny!
For Sam Darnold of the Seahawks all players in the Super Bowl will individually earn the same amount. Winning players will be paid $178,000Welcome to California, land of Democrats. You got money? Gimme, gimme!
Darnold’s bill to the Golden State will be $249,000. The outlet stated the sizable check is due to California’s “jock taxes,” which force pro athletes who don’t live in the state to fork over percentages of their yearly income based on the number of days they work in California.
And here's Oregon. Lawmakers want to lower the cost of building affordable housing. Sounds good, right? But there's this prevailing wage law, which mandates that contractors pay union wage rates to workers on publicly subsidized projects. SB 1566 wants to change that, as union wages add 10% to 20% to project costs. So will they piss of labor unions, or give up trying to do the right thing?
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What's the second most valuable company in Oregon after Nike? It's Lattice Semiconductor. Yeah, I'm surprised, too. AI is what brought it back.
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Semaglutide ameliorates osteoarthritis progression through a weight loss-independent metabolic restoration mechanism. Wow, it can actually promote cartilage restoration as well as help you lose weight. If it comes with any more benefits, we might have to put this in the drinking water.
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Two related articles:
Living in the inflection point: "It’s scary because I don’t know what the future of my own job looks
like. A skillset that was previously highly valued is now much easier to replicate with AI tools."
No one wants to admit the real reason corporations are laying off thousands: "If you are a corporate employee whose job is reliant on a computer, there is a high probability that you will someday be replaced by AI. This will happen. But there is something you can do to avoid this fate: Be valuable."
Rather than crank out code to meet the needs of some company, it's time to look around the world and see what problems need solving and use AI tools to start fixing them. Be valuable.
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Down the slippery slope they go. California Wants Gun Blueprints Treated Like Weapons. The excuse to take away a right is always "to protect the public".
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Bloomberg has this article: How to Tax a Trillionaire, and says that politicians need to find smarter ways to do it because extremely wealthy people will always find a way to escape. But it's clear that the author is pro-tax. He concludes with
After all, as Supreme Court Justice Oliver Wendell Holmes Jr. once put it: “Taxes are what we pay for civilized society.”
Yeah, well despite all the taxes we pay, we're not getting anywhere near a civilized society. I repost this meme:
––– 良くない––– Speaking of finding a problem the world has and figuring out to solve it, I came across this article: ReMemory Is The Amnesia-hedging Buddy Backup You Didn’t Know You Needed. I clicked because I didn't know I needed it either. It's a system where you break up an important secret into several pieces and give each piece to several friends. Only by putting together each component can the secret be revealed. Clever, huh? The author even supplied the code for this. But as the commenters say:
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Just hope you remember which tool you used for this, and which friends you picked to hold the secret.
And hope your not ghosted by your /friends/.
And that your friends themselves did not forget or lost the piece of information they should retain.
Some hacker tips, which I will probably never use. I'm seeing IVPN come up again. Maybe I should give them another look.
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2 to 3 Cups of Coffee a Day May Reduce Dementia Risk. But Not if It’s Decaf. Ordinarily I don't click on NYT articles, because I don't have Gell-Mann Amnesia, but I wanted to see that dataset. The study population was 100% women over 70. The "No Kings" protestor crowd! Drink up ladies!
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Problems we didn't know we had. The world is suffering from a shortage of tenors. Holy smokes, what shall we do? Thank goodness for AI, right? 😂
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Math, Inc. and AI for Science. Now THIS is the kind of research the government needs to fund. Not the Harvard or Stanford crap.
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The hidden link between blood sugar and anxiety. Maybe Till Brönner and Bob James were right? "The sugar melts away the loneliness. Make it nice and sweet!"
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The US Is Flirting With Its First-Ever Population Decline. Bloomberg tries to blame it on Trump's deportation policy. Nope. Obama deported more than Trump and there wasn't a decline then. What's happening is a stark drop in fertility, and guess what's causing it? I have my suspicions.
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National Cancer Institute studying ivermectin’s ‘ability to kill cancer cells. I gotta agree with the critics on this one. I don't think it's the best use of funds to spend to see if ivermectin can be repurposed as an anticancer agent. Oncology therapeutics is going beyond the old repurposing or screen-everything days. In the age of GenAI and other advanced drug discovery tech, there is no need to revisit ivermectin, especially when there is no compelling preliminary data.
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I saw this article: Do women really select for intelligence?. And then I read this article in the WSJ: A Stanford Experiment to Pair 5,000 Singles Has Taken Over Campus. Apparently its attracting a lot of attention, as new things often do. But it's not clear that people are getting hook-ups as a result. The data show that good-looking men score. Nerds generally don't. What women really seek is success, especially financial success. That's more than just intelligence.
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Really sad. Portland’s 20 largest office buildings have lost $2 Billion in market value since 2019.
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Which American city spends the most on homelessness? Turns out, there's no actual study to obtain an answer. But I would bet that for per capita spending, Portland and Seattle would be up there.
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Happy Anniversary! 🎉 This is the third anniversary of this little blog.
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AI fatigue. One coder is experiencing AI fatigue. It's easy to generate code with the use of AI. But then you have to review it make sure it's valid and with no vulnerabilities, etc. Maybe this is why less than half of AI-generated code gets reviewed, and most AI engineers don't trust it. And in healthcare AI, this can have serious consequences: As AI enters the operating room, reports arise of botched surgeries and misidentified body parts. Looks like the tech industry has stumbled into AI too fast, instead in a controlled carefully considered manner. The fear of being left behind can be crazy.
Hollywood is losing audiences due to AI fatigue. Yeah, I was disappointed at the last Mission Impossible movie, too. I can suspend disbelief, but not that much. Here's a Chinese video streamer who's surprised that the latest AI tools have trained on the material he puts out. Imagine that, a Chinese guy surprised that Chinese tech companies will copy and use his intellectual property without his permission! Who coulda thunk it?
And even Waymo admitted that its AI depends on their being Filipino backup workers to drive their "autonomous" vehicles when the AI fails. Not the first time this has happened.
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This is how the X algorithm works. How you get boosted. Or shadowbanned. It's a gameshow.
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That paper that came out showing that time of day matters a lot on the survival outcome of chemotherapy has gotten intense scrutiny. There's some reasonable criticism. It doesn't seem to make sense that just by giving chemotherapy in the afternoon, you lose all the survival benefit of treatment when the antibody itself lasts a long time. Some question the flow cytometry and I don't have expertise to critique that. But the reviewer seems to think that the latest paper is actually on the same population as the earlier 2025 paper, which doesn't make sense because the 2025 paper went out to 44 months, whereas the recent paper only went out to 34 months.
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Vermont EV buses prove unreliable for transportation this winter. I think EVs really only make sense for sunny climes like the Bay Area where you have working charging stations everywhere.
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Blood omega-3 is inversely related to risk of early-onset dementia. Although not explicitly stated, it seems that the most important components in this are the non-DHA components, namely Alpha-linolenic acid [ALA], Eicosapentaenoic acid [EPA], and Docosapentaenoic acid [DPA]). So look for products that have more of these.
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Epstein files reveal deeper ties to scientists than previously known. So many people were entangled by the lure of money and underage sex. Even scientists were not immune. But what is this thing with jerky?
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A chill brain-music interface for enhancing music chills with personalized playlists. It's unusual to see an article on how to experience music that gives you chills in the journal Cell. This tech uses EEG information to create a neurofeedback system that uses an in-ear electroencephalogram (EEG) to create personalized playlists. The EEG-updated pleasure-enhancing playlist elicited more subjective chills and higher pleasure ratings than the pleasure-reducing playlists,
suggesting that adapting music selection to individual neural activities can amplify chills and emotional engagement with music. I'm game to try it.
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Yeah, history tells us that selectively taxing the very rich isn't going to be successful.
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Japan Makes History by Beaming Electricity From Space Back to Earth. This is novel. To collect solar energy and beam it down to earth. Wonder if that really pencils out. Sugoi, if it does.
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Apple silicon Macs have 2 types of Thunderbolt ports. But they're not labeled, and sometimes they're on the left, sometimes on the right. Who knows.
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The City of Los Angeles is suing the state of California regarding the Pacific Palisades fire. The City of Los Angeles filed a cross-complaint against the State of California seeking indemnity and contribution for the fire victims' claims against the City. I knew it was about money.
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AI fails at freelancer tasks 97% of the time, new 'Remote Labor Index' shows. This is what I see, too, and may give some comfort to coders. Writing good software is not simple and not something that can be done as easy as some of the apps would have you believe. But software is getting better, so one shouldn't relax. AI Makes the Easy Part Easier and the Hard Part Harder is a good way of putting it. But yeah, it'll probably kill a lot of those remote Indian jobs. Simple and often shoddy work now can be done here at home.
And I've had this FOMO feeling sometimes, where you think that everybody's getting on the Clawdbot game and you're not, and you must be so behind. Glad to know that I'm not the only person feeling this way, and that it's essentially hype and delusion.
I agree with this guy that software engineering is on track to get to the next level. I don't call it "vibe-coding". I call it "coding assistance".
Microsoft needs to figure out what it wants to do in the AI world. Google has figured it out. Anthropic, too. Apple is taking action to serve its customer base. But what does Microsoft have to offer that's better than alternatives?
This guy has a clever way of getting around deepfakers who post videos of him saying false stuff. It's not scalable, of course, and it would be a lot easier if he just displayed a hologram containing the date, or something that wouldn't be easy to deepfake. The struggle continues.
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A lot of people seem to oppose ICE, but I am glad that they are extracting these people from American society. You know that if Kamala Harris won, these folks would still be running free.
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China’s ‘artificial photosynthesis’ method could create petrol from carbon dioxide. When life give you lemons, make lemonade.
And from Montreal, comes a new organic molecule, AzoBiPy, that can store electrical energy for months with almost no degradation, offering a promising path toward better large-scale energy storage. It can substitute for lithium in fuel cells. Certainly safer than hydrogen fuel cells.
Japan's PM Sanae Takaichi is predicted to win the recent election in a landslide. I think the Japanese took a look at what's going on in the U.S. and Europe, and have seen enough. None of that diversity crap. Who can blame them?
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Ovarian cancer is indeed somewhat unique in the way it spreads in the abdomen. It spreads like wildfire, taking over the surface structures. Now we know why and it involves TGF-β. Seems that a lot of undesirable conditions in the body are connected to TGF-β.
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Why bitcoin is losing its luster. Gold is better. I think that Trump himself may have hastened its demise. The creation of Trump Coin and Melania Coin revealed to everyone that crypto is just a joke.
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High estrogen levels in brain may increase women's risk of stress-related memory issues. Well, in mice anyway.
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Oregon’s Education Workforce Climbed While Student Enrollment Slid. The state added nearly 12,000 employees since 2020, but school districts face layoffs as budget cuts loom. Lowest rank in the nation. As a commenter said: What's the point of all these articles?
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Seems like a lot of people are talking about Mark Hemingway's hit piece on Portland that came out on Real Clear Investigations. Even some Lefties are saying that it's true. All Portland leadership needs to do is
- Get the homeless off the streets. Make it not worth their while to set up camp in the region. Stop trying to install them in various parts of the city with shelters and rehab centers and crap. It's not working.
- Get tough on crime. Jail and prosecute criminals, including the drug dealers and drug users.
- Start spending money to the benefit of the actual taxpayers. Clean up the city and make it beautiful again.
We might be able to see a great comet in April. A Kreutz sun-grazer, C/2026 A1 (MAPS), is on the way. We're long overdue to see one of these. Comet West (1975) was very impressive. Even Comet Bennett (1969) was very nice. It's strange, because another comet, C/2025 R3 (PANSTARRS), is scheduled to make an appearance in April, with a magnitude of 0.4. So will we get two bright comets close together, like Hyakutake (1996) and Hale-Bopp (1997)?
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Do rich people live longer? Yes. Not just because they have better health insurance. They eat better. They have more leisure time to exercise. They're smarter and don't do stupid things and know better how to assess risk and handle it.
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The Search Engine Map. Wow, Bing is bigger than Google. People do rank their search results as being the best now. The Google search universe is smaller – how the mighty have fallen. Competition is good.
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Wow, I hadn't heard about ostarine before. It's a hormone-like agent that mimics the desirable effects of testosterone and anabolic steroids — including muscle growth and increased bone mass – without other negative effects of testosterone. Of course, it's now a performance-enhancer that athletes dope themselves with.
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The Stanford scam proves America is becoming a nation of grifters. And it's not just the students, it's the timorous faculty that allow it to happen. Such sheep. They knew about it, and refused to get involved in the scam.
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SCoR2 is a denitrosylase enzyme that regulates lipogenesis and fat storage. I predict we'll see seeing even more important research coming out soon regarding SCoR2 and drugs to inhibit its action.
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Anxiety about the impact of AI on software development is not going away. I'm playing around with Claude Code 4.6 and seems to be very good, although I haven't really given it hard stuff yet to see how much better it is over the previous SOTA model. I agree with Jensen Huang that people are over-panicking. It won't be that easy to clone Oracle, but what it might do is give companies the opportunity to be less dependent on large enterprise solutions. Hard to say what the fallout will be at this time. But the software kings will have less leverage, for sure.
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Ugh. Google workers want to restrict access to Google Cloud services for immigration enforcement. This is what happens. Google hired foreign-born immigrants in the name of diversity. Now they want to determine domestic policy and hamper governmental agencies. We need to enforce our borders or we lose our geopolitical integrity. It's as simple as that.
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This article says that anti-vaccine tweets caused people to get sick and some to die because they didn't get the vax. Hey, what about the lives saved because people didn't get pulmonary embolism, die of sudden cardiac death, or get turbo-cancer? Did you count those people?
It's important to remind people of the kind of bullshit we were subjected to. Here it is:
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Every major galaxy is speeding away from the Milky Way, except the Andromeda Galaxy, which is on a collision course with us. Better eat desert first. It's dark matter!
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Oregon Supreme Court Ruling Leads To Dismissal Of More Than 1,400 Criminal Cases Statewide. This is so under-reported. Oregon can't convince enough lawyers to move to Portland and can't graduate enough competent lawyers to practice, that we're letting felony crime perpetrators go free. How's that for a functioning state?
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The world is healing. Oregon advocates drop ballot measure that would secure rights to transgender health care, abortion, same-sex marriage. They wanted to put grooming and pro-pedophilia laws into Oregon's constitution. I know it's on-brand for Oregon, but still.
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New poll shows that Oregonians think that economic conditions in the state are getting worse. We have a long way to go.
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Portland wanted to raise taxes, but suddenly somehow, Portland is sitting on $106 million in unspent housing dollars. They really wanted to expand their slush fund. All that housing money, and nothing is going to improve.
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This is unethical. To subject poor people to view disturbing content just so that AI can classify it correctly. We are scarring people's brains permanently.
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'The EU runs on Microsoft' – and Uncle Sam could turn it off, claims MEP. Theoretically true, but very unlikely to happen. It would be suicidal for Microsoft to do it.
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Yes, it's true. Male brains differential from female brains in the womb in a detectable and measurable way.
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An oral PCSK9 Inhibitor, enlicitide promises to reduce dependency on statins. We have the injection form, but that's not as convenient as a pill.
But then the Lancet published a meta-analysis which found that all the weird off-target side-effects of statins, such as cognitive impairment, depression, sleep disturbance, and peripheral neuropathy, were not substantiated. So all's good, then?
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Well that's not good. ‘Starlink killer’: China’s 20 GW microwave weapon could fry satellites with 60-second bursts. This could lead to another arms race, which would be catastrophic. Not to mention the Kessler syndrome effect, which would set space travel back for decades at least.
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California universities are spending $17 million to provide ChatGPT for students. That's such a poor way to spend money. It doesn't make them smarter and just sets them up for privacy violations, maybe legal trouble, maybe psychosis, maybe other trouble. Because it likely won't come with a course on how to use it. Better if they got access to a creative suite like Poe.com.
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California Dems are apparently terrified that the wealthy tech elite are fighting back against the billionaries tax. They thought those guys would always be in their pocket.
And up in Washington state, it appears that billionaire Nick Hanauer, who was in favor of the tax, actually doesn't domicile in the state of Washington, so the tax wouldn't apply to him. Dick move, Nick.
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TSMC is going to build new 3 nm chip factories in Japan, which would help both parties. Good for Japan, but why not the U.S.?
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Don't you hate when that happens? You invest in expensive solar panels, and the company disappears. Prolectric LLC took people's money and then vanished. Solar needs subsidies, or else it doesn't pencil out.
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Scientists Identify Key Protein That Could Reverse Brain Aging. Nice. Let's develop it. Put it to use.
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Fat chance. Tina Kotek wants Trump to stop enforcing immigration law. Why? Because illegal aliens are scared. She wants a state governed by the rule of feelings, instead of rule of law. "No one is above the law" is something only conservatives must follow.
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Lloyd Center will vanish into Portland's memory hole. Like a lot of other things, the city can't support nice things. So it'll be torn down. And I strongly doubt it will look like the picture in the article. Add several tents and graffiti on the walls. And there will be no open cafés. Windows will be boarded up. Also lots of trash and people bent over. And everyone will be wearing backpacks.
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