This recently-published paper is getting attention amongst oncologists. A 60% reduction in cancer mortality just by getting your lung cancer chemoimmunotherapy in the morning instead of the afternoon. It's actually a follow-up study on data this group published a year before, with follow-up going to 48 months. This time it's data from the phase III LungTIME-C01 trial going out to 34 months, and the spread between morning and evening chemo time survival is stark.
Betrayal
And in Bellevue, Washington, students at Newport High School cut class to protest in the streets. You'll not find this coverage in regular mainstream news. What crap! Would society have tolerated this ten years ago?"Oregon’s poor student performance is not due to lack of funding. It’s driven by:
Money isn't going to fix this.
- Low attendance
- Short school year
- Inefficient spending
- Administrative bloat
- High pension costs
- Deep socioeconomic gaps
- Weak accountability"
Of course, even those who yearn to visit or live in a walkable, dense neighborhood are not going to flock to a place surrounded by a grim urban dystopia. Efforts to address downtown’s dysfunctions will elicit the usual cries from progressives, who seem unwilling to carry out the necessary policing. But if L.A. and other cities want their downtowns to survive, this should be the first order of business.
Family document filing. I send a PDF or photo via WhatsApp. Lollo analyzes it with vision-document type, date, sender, amount if applicable. Photos get converted to PDF, then run through OCR. Files are renamed according to a consistent schema (’YYYY-MM-DD [Sender] [Type] [Details].pdf’) and sorted into the appropriate folder. The whole pipeline-vision analysis, format conversion, OCR, renaming, filing-happens automatically.
But filing is only half of it. The retrieval is where it gets interesting. “What insurance policies do we have for our toddler?” “How much did we spend on contractors in 2025?” Lollo searches the archive, reads the relevant documents, and gives me an answer. The documents aren’t just stored—they’re accessible in a way that actually matters.
Personal color consulting. I had professional color analysis done. The results—which colors suit my skin tone, which to avoid-now live in a dedicated skill. I send a photo of a sweater I’m considering: “Does this work for me?” Lollo checks it against my profile and gives me a straight answer. The knowledge persists. I don’t have to explain my color type every time.
Proactive scheduling. Every morning at 7:45, Lollo sends me a briefing: today’s calendar, weather for dog walking times, anything that needs attention. I didn’t ask for it. It just happens. The night before trash collection, I get a reminder which bins to put out. Once a week, I get a summary of local news, filtered by our interests and delivered with a Rhine-region commentary—my wife and I are expats from the Rhineland living in Bavaria, and Lollo knows to add the appropriate sardonic undertone.
Ideas and todos. When I have an idea, I say “new idea about X” and it goes into my Obsidian vault, properly formatted, synced. When I need a todo, same thing. The knowledge doesn’t get trapped in a chat history I’ll never scroll back through. It flows into real systems where it belongs.
Watch history and taste. Lollo has access to my Trakt.tv data-everything I’ve watched, when, how I rated it. Over time, this becomes a taste profile. Recommendations get better because they’re based on actual behavior, not a cold-start conversation.
Meal planning and culinary consulting. Forget smart fridges. I tell Lollo what’s in our pantry and fridge-on the go, via voice, whenever I remember. Not everything, but ingredients that survive a week’s cooking cycle. Based on what’s actually there, it suggests dishes that match our preferences.
Contact management. After meetings or on the go, I can quickly dictate the people I just met. Mixed with photos of business cards, LinkedIn profile links, whatever I have. From this mess, Lollo creates clean new contacts or updates existing ones.
A recent article in The Atlantic reported that an increasing number of students at elite universities were claiming they had disabilities to get benefits or exemptions, which can also include copies of lecture notes, excused absences and access to private testing rooms. Those who suffer from “social anxiety” can even get out of participating in class discussions.What kind of student is Stanford admitting these days? They learn to grift at that school.
Effective January 1, 2026, Washington State is increasing the advanced computing B&O surcharge from 1.22% to 7.5% for select companies, per HB 2081.
Effective January 1, 2026, through December 31, 2029 , Washington state imposes a 0.5% Business and Occupation (B&O) surcharge on businesses with annual taxable income exceeding $250 million. This additional tax applies to the amount of taxable income over $250 million and is separate from regular B&O taxes
Chief U.S. District Judge Richard Seeborg denied the request to order Google to disgorge $2.36 billion in alleged profits and to stop certain ad-related data practices.
Google countered that an order blocking it from collecting users' account-related data would “cripple” an analytics service relied on by millions of app developers.
Seeborg ruled that the plaintiffs failed to show any “prospective, irreparable harm” that would justify a permanent injunction barring Google's data collection practices.
The predominant finding was positive feedback, but inaccuracies were commonly reported. When information was inaccurate, we found that missing information and confusing information was more commonly reported than hallucinations. While hallucinations are a well-characterized problem with AI-generated note summaries evaluated previously, our study suggests that errors of omission may represent a larger threat to the accuracy and usefulness of AI summarization tools than errors of commission (i.e., hallucinations). Together, these results indicate that the AI-enabled LLM note summarization tool was felt by end users to be clinically useful, while underscoring the need for improvements to prevent omission of pertinent clinical details.
A new study reports that a triple-targeted drug combination can drive complete and lasting regression of pancreatic tumours in preclinical models, potentially overcoming treatment resistance in one of the deadliest cancers.
Researchers at the Spanish National Cancer Research Centre have announced a potential breakthrough combination therapy that induces complete regression of pancreatic tumours and prevents tumour resistance in preclinical models.
Paper here. The drugs they used were:
- RMC-6236 (daraxonrasib): targeting KRAS
- Afatinib: an EGFR family inhibitor
- SD36: a selective STAT3 degrader
Maybe Earth will have a ring in my lifetime after all.A "close approach," defined as two satellites coming within less than 1km of each other, happens about once every 22 seconds. Within the Starlink network alone, this occurs roughly every 11 minutes. To avoid collisions, each Starlink satellite must carry out an average of 41 course corrections every year.
Solar storms can interfere with or disable satellite navigation and communication systems altogether. When that happens, satellites may be unable to respond to threats in their path. Combined with higher atmospheric drag and increased uncertainty, this loss of control could quickly lead to a serious accident.
The most widely known outcome of widespread satellite collisions is Kessler syndrome. In this scenario, debris from collisions accumulates around Earth, making it nearly impossible to launch spacecraft without them being destroyed.
Celibacy taught me I’m too clever to find love. Too clever? No wonder his girlfriend ditched him.
And speaking of people who get burned using tech that they don't fully understand, here's a three-parter on those who jumped onto the Clawdbot craze.