Nature reports the results of the AMPLIFY-1 trial: Lymph node-targeted, mKRAS-specific amphiphile vaccine in pancreatic and colorectal cancer. I note that this is only a phase I trial, so they can't really comment about efficacy. Also they used peptides as antigens, not mRNA, which is a good thing. Mutated KRAS has been an "undruggable" target since it is not an external protein, and it is upstream of very important signaling pathways.
––– 凄い –––
An infectious disease expert at Stanford is not convinced that the mRNA vax is a bad thing. He seems to base his argument on the credentials of the people who put Kennedy's report together, and not as much on the report itself. And he puts a lot of importance on the data that was published in journals at the time, not acknowledging that you pretty much couldn't say out loud that the vax wasn't working, or should be paused, or else your manuscript likely wouldn't get published. I also don't fully trust the published studies that show that the vax saved lives, since much depended on how the disease was defined and when they started counting (after the first shot, after two shots were given, thirty days after the second shot, etc). People who died from the vax itself often didn't get included.
––– 良くない–––
The Tragedy of the Computer Science Major. I think that those with a CS background who then take AI classes are the best. The author suggests getting a job in a non-tech firm. Many are doing this, and it can work out.
––– 凄い –––
Provide sloppy code to an AI and it becomes evil? These days, it seems that it's so easy to make an AI model go evil. But not so easy to turn them around.
––– 良くない–––