Asundexian looks like a winner in preventing secondary strokes and heart attacks without increasing risk of bleeding. It's an oral inhibitor of activated clotting factor XI, which is not a critically important clotting factor. People that are deficient in it don't have major problems like those with hemophilia, although risk of bleeding with surgery is increased. Asundexian is not yet FDA-approved.
The incidence of ischemic stroke was lower in the asundexian group than in the placebo group (6.2% vs. 8.4%; cause-specific hazard ratio, 0.74; 95% confidence interval [CI], 0.65 to 0.84; P<0.001).
The incidence of the composite of death from cardiovascular causes, myocardial infarction, or stroke was lower in the asundexian group than in the placebo group.
The incidence of major bleeding was similar in the asundexian group and the placebo group (1.9% and 1.7%, respectively; cause-specific hazard ratio, 1.10; 95% CI, 0.85 to 1.44).
The incidence of adverse events was 69.3% in the asundexian group and 70.1% in the placebo group.
The incidence of serious adverse events was 19.2% and 19.5%, respectively.
People have noticed that small towns in Lebanon no longer show up in Apple Maps. Apple came up with a rather surprising explanation: "The blanked areas were never part of the detailed Apple Maps experience from the onset. This means the app’s upgraded version is yet to be available in the southern Lebanon region." Ah, I see – they need to upgrade to the new Apple Maps experience. I'm gonna save that one and use it in the future...
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Radiologist cannot distinguish real from ChatGPT-generated radiographs. Misuse of this could include fraudulent images used in insurance claims, litigation, or Munchausen syndrome, and the fact that one in five AI-generated radiographs escaped expert detection in our study highlights this vulnerability. Radiology departments may soon have to implement digital watermarking, cryptographic hashing or blockchain-based ledger systems. Healthcare is gonna get more complicated (and expensive)!
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Elon Musk was pushed out at PayPal. Now he’s launching a rival that could ‘disrupt’ it. Not sure I trust Elon with my money, but I don't want to support the woke PayPal. I also want to see sites offer this as a payment option. But competition is good.
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The carbon monoxide laser briefly heats the surface, breaking down cellulose, hemicellulose, and lignin into smaller molecules. These don’t disappear, they remain on the surface as what researchers call ‘fusible cleavage products.’ Think of them as a kind of built-in glue, created on demand.
Yet another study about how bad AI is for our brains.
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We find that AI assistance improves immediate performance, but it comes at a heavy cognitive cost,” the study declares. Researchers went on to state that just ten minutes of using AI made people dependent on the technology, which led to worsening performance and burnout once the tools were removed.
A cascade of failures. A couple of enterprising prisoners carried out a hacking operation in prison. Amazing.
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How Secure Is Tap To Pay? VISA is unwilling to fix the problem. The excuse is that because they haven't see very many attacks using this exploit, it's nothing to worry about. That's a piss-poor attitude. The guy should not advance to higher management levels.
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Get the word out. They're lying to you about nuclear energy. Everyone should see this video, especially those in the government. It's so important to estimate risk accurately. If you underestimate risk, you might get hurt or killed. If you overestimate risk, you make poor, uninformed decisions, like this. Nuclear is the way to go. Although I don't recommend eating uranium.
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Friends Don't Let Friends Use Ollama. I feel like an idiot. Been using Ollama all this time because I like private local source models. But it adds an extra layer, and there's a version of open source models that takes advantage of my Apple silicon – the MLX models. Oh well, live and learn.
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Did you know that Oregon tops the nation in the number of sex offenders? Here's one that a judge wants to put on house arrest.
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Music Millennium Cancels Listening Party After AI Backlash. Doesn't this seem silly? Canceling the party won't make AI-generated music go away. Whatever. You do you, Portland.
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