Ponsegromab is an antibody against GDF-15 (growth differentiation factor-15) and inhibition halts the severe weight loss, anorexia and decline in physical activity seen in patients with advanced cancer. There is a potential treatment using this antibody that may help improve the quality of life of cancer patients. (I just wish it weren't Pfizer that's developing it, though.)
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Ten-year follow-up on the CheckMate-067 study was recently published, and the improvement in survival still holds. No surprises there.
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MacOS 15 (Sequoia) is out. I remember the days when Apple's stock rose when they came out with new stuff, as people were excited and sales soared. Now Apple's stock sinks on the disaapointment. The ArsTechnica review makes it sound like more of a 14.6 version than a 15.0 update. Looks very minor. The AI stuff isn't ready and is expected to roll out later this year. So nothing that's truly new and transformative. Just incremental improvements.
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Throwing good money after bad. Measure 118 just steals money from large corporations and essentially scatters it over the state. And everyone, including criminals, can have some of that money. Oregon is the nation's leader in really dumb ideas.
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