This is noteworthy: First RAS Inhibitor Extends Survival in Previously Treated Metastatic Pancreatic Adenocarcinoma. It's daraxonrasib, a pan-RAS inhibitor. It's not only effective against pancreatic carcinoma but also against other RAS-mutant tumors. RAS has been hard to target since it's an intracellular protein. This drug works by forming a complex with an intracellular chaperone protein CypA, an inhibitor, which blocks effector binding. This is great, because so many cancers are caused by mutated RAS. Could be a real breakthrough. Side-effects are kinda nasty, though, but perhaps there will be a way to mitigate those, as with the EGFR inhibitors.
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High intelligence is not associated with a greater propensity for mental health disorders. Well, that's nice.
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Well, after posting about the death of the small liberal arts college, comes this article saying that they are the "accidental winners of the was against Higher Ed". But what they're really saying is that since those colleges don't have a research department, they don't have to worry about research funding cuts that others have to endure. It's not really something to feel good about, though. They're not "accidental winners". More like "accidental non-losers".
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Noodlist has a site that rates the top instant ramen packages. There are better ones, though, but only available in Japan.
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wordfor.xyz is a reverse look-up dictionary. But really, why would you need to go to this website? You can just look it up in any chatbot. It's based on an open-source model but seems to RAG on a bunch of different dictionaries. You can see when you first go to the website. Update: I just entered the definition for Abilene Paradox, and it did not give me the term I was looking for. But Claude did. Meh.
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Here's a site that lists many of Generative AI's notable fails. You don't want to be on this list.
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Japanese researchers find a simple way of making hydrogen from alcohol by using iron and UV light. This is fantastic. If they can generate hydrogen so cheaply, then it greatly reduces the cost of hydrogen fuel cells. And if the process could be amplified, maybe we could just power up on methanol, and generate hydrogen when we want to. It would be hell of a lot safer than transporting hydrogen gas.
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Here's a first glimpse at the interior of the Ferrari Luce, designed by Jony Ive. Looks like an Apple car.
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The scientific case for being nice to your chatbot. ...a recent paper from Anthropic lends scientific weight to the theory that chatbots work better when you’re nice to them.
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How a Non-Theorist and Two AIs Proved a Theorem: Anatomy of a Human-AI Collaboration in Mathematical Economics. This is how to use AI, to enhance your own abilities. Love it!
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Scientists Just Created Super-Strong Printable Steel That Never Rusts. Imagine that you can use a 3D printer to create things. This will be revolutionary.
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Has New Music Become Less Popular? It seems so. The stuff I hear pumped out through speakers at the mall are not memorable.
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