Sugoi & Yokunai

CRISPR Breakthrough Could Rewrite Future of Genetic Disease Treatment. I remember attending a lecture given by Dr. Jennifer Doudna after she won the Nobel Prize. Now instead of just editing genes, we can edit epigenetic elements, such as on histones and CpG islands. Truly, her breakthrough discovery has made a huge difference in genetics.

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The comments in this article are revealing. It's about how state tax laws are appealing to private equity investors. But many of the commenters decry investors wanting to keep their own money. "Why can't it taken away by the government so they can spend it?"
they cry. I don't understand some people. So it's greed to want to keep your own money, but it's not greed to demand a share of others' earnings? Crazy.

Then there's California, which seems to be going forward with their unrealized gains tax on billionaires. The bill is obviously written by people who know nothing about finances.

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When Waymo's robot taxis get stuck, a secret army of humans comes to the rescue. 

Heh, the world is not ready yet to discard human labor.

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Americans hate AI? It's more like most Americans don't really understand AI. Or don't want to understand AI. Because if you do, there are opportunities.

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Blue State blues. New business model drops in Seattle.  And Katie Wilson hasn't even assumed office yet. Oh boy.

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Portland office sales will drive millions in property tax losses: year in review. This statement me chuckle:

New owners of downtown buildings won’t have negative equity, shorthand for when borrowers owe more money on a property than it’s worth, also known as being “upside down” on a mortgage. 

What makes you say that they won't have negative equity? We're not at rock bottom yet.

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And Seattle no longer tops big cities for share of tech workers.  And there goes the wealth. It's no longer worth it to work in Seattle.

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