30 November 2025

In a proof-of-concept study, medication deiivered by intranasal drops were able to activate the STING pathway in murine glioma tumors. This may be a way to deliver certain treatments directly to intracerebral tumors.

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Only a third of Americans now see college as being worth the cost.  I fully agree. Most people haven't saved enough for college. Why go into incredible debt at usury terms, just to be woke-indoctrinated and come out with knowledge that still isn't enough to secure you a good job. Who woulda thought this a few years ago? 

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Handwriting recognition has gotten really good lately, especially with Google's latest Gemini model (the Pro 3).

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The automated glassbreaker you have in your car is now ineffective against the newest laminated glass.  There's still no tool out there that will break laminated glass. This is an unmet need.

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Startups are finding out that anyone can use AI to copy their idea. That's what happens with low barrier to entry apps.

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A group of metabolites, known as indole compounds, has anti-aging, anti-inflammatory and antimicrobial properties, and a bacteria is capable of producing them. The bacteria is  Paracoccus sanguinis.  Is this true? Why haven't I heard of this before?

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A reminder that the illusion of consensus is powerful. Just because most people think something is true or the right decision doesn't mean that it is. Think of COVID-19 policy. Not only might it be wrong, but it may be an instantiation of the Abilene paradox. Don't be fooled.

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Most children identified as gifted at age 7 do not maintain high cognitive ability by adolescence
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Nursing Is No Longer Counted as a ‘Professional Degree’ by Trump Admin. I'm not sure how this will really affect the number of nurses that we will have. Nursing has changed a lot over the years, and nurse practitioners function similarly to doctors. But one thing that distinguishes nurses and nurse practitioners from doctors is that they unionize and strike. Real professionals, like doctors and lawyers don't strike and abandon their clients. This is something that the labor class does. By unionizing and striking, nurses debase their profession, and put themselves in the same group as those who are plug-and-play replaceable.

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A primary motivation for the trial was the high content of L-arginine found in peanuts. L-arginine is an amino acid that serves as a precursor for the synthesis of nitric oxide, a molecule essential for relaxing blood vessels and regulating blood flow.

Additionally, the study focused on skin-roasted peanuts because the peanut skin is rich in bioactive compounds, including polyphenols like resveratrol, which have antioxidant properties that may further support vascular health.
Arginine again. Not sure if resveratrol does much. Studies of this drug haven't held up.

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Oregon's median income has increased, but growth of the economy has lagged behind. Seems counter-intuitive, but the answer is that income has increased because of strikes and union-demanded pay increases. This actually hurts business and keeps the labor market soft. Not that anyone cares in this state.  Gas prices around here remain high, and will increase if the Transportation Bill stays into law. But in other parts of the country, the price of gas has decreased below $2 /gal.  And people are starting to take notice.

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Sick. The Oregon Health Authority, state of Oregon, are sending out questionnaires to sixth graders asking them their sexual identities and sexual orientation. This is depraved. What sicko decided this was appropriate. And why aren't parents protesting?

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And Portlanders wonder why apartment construction has come to a halt in the city.  It isn't just the Urban Growth Boundary anymore. Think about it. Who would care to spend the money to build new apartments in the city limits? Only a fool, that's who.

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