5 February 2026

This recently-published paper is getting attention amongst oncologists. A 60% reduction in cancer mortality just by getting your lung cancer chemoimmunotherapy in the morning instead of the afternoon. It's actually a follow-up study on data this group published a year before, with follow-up going to 48 months. This time it's data from the phase III LungTIME-C01 trial going out to 34 months, and the spread between morning and evening chemo time survival is stark.

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I did a double take on this:  Scientists Discover Gut Bacteria Can Inject Proteins Into Human Cells. How long has this been known? Is it any wonder why there is an alarming rise in colon cancer in the young, with all those E. coli producing colibactin?

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Sign of the times: Japanese city cancels cherry blossom festival over badly behaved tourists. Too many assholes now. It's a global disease. They can't have nice things anymore in Japan. And I think this is why PM Sanae Takaichi was swept into office. 

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Claude Opus 4.6 was announced today. Can't wait to try it. 
And did you see Anthropic's Super Bowl ads targeted against OpenAI? Sam Altman was pissed about it. How many are there?
Betrayal
OpenAI needs money, and the ads were going to be a way for them to do so. If mockery shuts this down, then what? (Great work, Anthropic.)

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There's been a bunch of writing about what AI means for the software industry. The Fall of the Nerds, for example. Or Death of Software. Nah. I agree that if you already are a stellar software engineer, you will find that these AI tools will take you to the next level. Heck, I'm using them and doing things I never could have imagined doing before. It's like having a personal coding tutor next to you, available at all times. Yeah, there's a price, but it's well worth it.

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What a joke. Security firm finds Moltbook's 1.5M 'AI agents' run by 17K humans. Don't get caught up in the hype. A lot of times, it's never exactly what they say.

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Using AI, someone broke into AWS and gained admin access in 10 minutes.  See what I mean about how AI can take you to the next level?

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Portland Public Schools faces $50 million budget shortfall, calls for state help. Oh no! We've overpaid our teachers and now we have no money left over! Help! Will someone think of the union???
And Oregon sets new statewide standards to measure student success. As one of the commenters said:

"Oregon’s poor student performance is not due to lack of funding. It’s driven by:

  • Low attendance
  • Short school year
  • Inefficient spending
  • Administrative bloat
  • High pension costs
  • Deep socioeconomic gaps
  • Weak accountability"
Money isn't going to fix this. 
And in Bellevue, Washington, students at Newport High School cut class to protest in the streets. You'll not find this coverage in regular mainstream news. What crap! Would society have tolerated this ten years ago? 

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Up in Seattle, thieves keep stealing copper wiring, so light rail’s newest stretch to close for a day for electrical repairs. Rinse and repeat.

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Judge restricts warrantless ICE arrests in Oregon, finding threat of ‘severe harm’. Yup, it's that judge again. The one Sen John Kennedy tried to warn the U.S. about. Someone needs to educate this judge about "warrantless ICE arrests". No warrant is needed. 

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Oh crap. So Portland might be subject to the same chaos brought about by Waymo cars.  Keep those things in the Bay Area, please.

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Lawmakers Mull Dialing Back Funding for Medical Residencies. Wow, so there is money for illegal aliens and giveaways to the homeless, but no less money to give to supporting new medical residents? WTF, man, this is why we will have a shortage of physicians in the future. This is why we pay taxes! Not to have our good money thrown after bad. Supporting graduate medical education is one of the things that the State is supposed to do.

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Looks like Seattle has another nut-case fruity-loopy healthcare professional, just like OHSU.

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Honolulu is full of eateries. From nice restaurants to holes-in-the-wall. They're everywhere. And now they are feeling the pinch. It's hard to thrive when you live in a Blue state.

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