Lasso peptides may be a new class of antibiotics. Lariocidin B is a member of this class, and binds to ribosomes, much like other antibiotics we already have, like macrolides, but they interact at the 16S subunit, not the 30S or 50S subunits.
––– 凄い –––
MathStudio is a different kind of calculator, that's for sure. As a student, I would have had a lot of applications for this. As an old ronin, it's a diversion. I could use something like this for data analytics, though. Anyone know of anything like it?
––– 凄い –––
Meta dropped Llama 4 over the weekend, and I, too, got excited. But it's not on Ollama.ai yet, and I haven't gotten around to getting it from Huggingface. Seems like it's more like Llama 3.4 than a 4.0. The reaction has been "meh". The models are large, though, but apparently they haven't been trained that thoroughly.
––– 凄い –––
China has a lot of datacenters that were built in anticipation of a high AI demand, but that feel through. Don't blame DeepSeek, though. There's still room for a lot of research and growth. You think NVIDIA is saying that all the works has been done? Heck no. China could rent out all that metal for geek hobbyists in the world, but who trusts Chinese datacenters to run or host your stuff? No one, that's for sure. Only the Chinese would trust the Chinese.
––– 良くない–––
Must see. I think Kevin O'Leary has the right perspective on tariffs. The reporter typifies people who like to rev up the panic for the views. You have to have someone who knows how to play a longer game, because that's how you change the world. The tariff's have certainly gotten people's attention, and that's the first step.
––– 凄い –––
There's Portland, ready to raise taxes on businesses again to fill those recurring "budget gaps". And Portland's non-profits don't have enough money to provide free legal assistance to illegal aliens, now that federal money isn't coming in.
––– 良くない–––