12 January 2024

Chinese billionaire Chen Tianqiao owns 198,000 acres of land west of Bend. This is in one of my favorite places to hike and explore. Should this be allowed? Should there be a cap on how much land foreigners are allowed to purchase. I doubt any American could own land in the PRC.

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Microsoft and Apple are neck and neck for the title of the world's most valuable company. Microsoft has had forward-looking leadership.  The momentum that Steve Jobs set in motion has finally fizzled out.

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91% of small business owners say colleges are giving students 'unrealistic expectations' for life after graduation. College grads are surprised that no one wants to pay premium to buy what they have to sell.
Well, what are they learning in school? Kids in Washington state that have this teacher probably aren't learning anything useful.

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Now that the U.S. faces the real prospect of war, the Army wants white men. And they aren't getting enough. White men don't want to sign up.

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Banks, Oregon is doomed. It's like those towns in the east that were dependent on the steel mills, or auto manufacturing plants. Really too bad.

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Some Oregon voters want to just block Trump, and say they don't actually need to prove harm. We just don't like something, so you can't have it.

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11 January 2024

Thousands of Software Engineers Say the Job Market Is Getting Much Worse.  Even Google is cutting engineering positions. Not good.

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Majority of debtors to US hospitals now people with health insurance. Something is very wrong. Insurance is supposed to insure you against something like this. That's why it's called "insurance". Market forces are no aligned to fix this problem. Insurance policies need to be owned by the consumer, not someone else. That's why coverage is so expensive and crappy.

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10 January 2024

Europe may be heading for something unthinkable? Yeah, it's the NYT. Can't believe that the positions of the Left might not be popular. Heck, Germany is thinking about just banning a political party they don't like. Sorta like the U.S. When you can't win, cheat.

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A win for the Navajo. Looks like the Peregrine mission won't be landing on the moon after all.

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Petition 47 lives on. Soon, Measure 110 will be defeated.

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Forever Lonely. Getting paid to impregnate women? Yeah, it was a fraud, but to think that some young men believed it.

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ZIP bombs. Interesting concept. A 4.5 petabyte file can be zipped into a 45k file. Then when a hacker downloads this onto his computer and tries to unzip the file – BAM!

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The teen mental illness epidemic. Especially in females. Not enough is written about this, but it is so real. And I suspect this begets the rise in transgenderism. And it's not just teenagers – young adults are affected, too, so even younger teachers could be mentally ill, as we've seen. And since those afflicted don't see themselves as ill, this will be a tough problem to solve, especially since they want power and control, in the name of diversity and equity.

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The Rabbit r1. This is an innovative device. The current user interface we have on phones, with icons representing individual apps, came from the Windows interface. But is that the most productive interface. This is probably what Steve Jobs envisioned with Siri, but the tech was not advanced far enough to really make it happen. I get the sense that Apple should be doing this, and would, if Steve were still alive. Instead we were getting thinner phones with increase pixel density that after a certain point, no one could appreciate. And more emoji. And a VR diving mask that only a few will use. Nothing innovative, and this is why Apple stock price has fallen. No one is compelled to buy Apple phones anymore.
I don't really like the toy design of the r1. I would not have approached Teenage Engineering. Some think that the demo reel is staged, like Google's Gemini demo video. I suspect that's true, and will wait for version 2 at least. Still give it a "sugoi", though.

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Blue States can't stop taxing. So true. Tina Kotek is floating a $3 billion tax, and California wants a wealth tax, but one that is created not to tax Hollywood wealth, of course. Just everyone else. This idea came from an Asian guy, who should know better, since his parents immigrated from China. Why any billionaire would want to live in New York or California just baffles me.
Update:

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And people wonder why Japan wants to keep out certain cultures. This is why. If you can't respect others, you have no business being in places like Japan. That's why they can have nice things and we can't.  GTFO "Johnny Somali".

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And now criddlers have something else to spend their "stimulus money" – gas-station heroin. Get it while you can, folks. It's tianeptine, and it'll mess you up, but it's street legal at your local convenience store – for now.

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8 January 2024

Nearly 1 in 10 U.S. homes are worth at least $1 million, close to all-time high. In Portland, it's more like 6.7% (Man, even Tacoma is higher). Inventory is low, and there's still enough demand for homes that prices can be this high and people will still buy them. This is the Fed's doing.

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Crime Rate by State. Oregon is 9th in the nation, and I bet that if you removed the City of Portland, it would drop down dramatically. And Oregon is 3rd poorest in the nation when it comes to income left over after taxes. Is there ANY good news about Oregon these days?

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The Crypto Con. This situation in Texas is crazy. So far, there hasn't been any plans to develop a crypto mining company in Oregon (that I know of). These mines consume so much energy, and the greenies aren't even aware. It's off their radar.

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Universities are not on the level. There has been an insidious decay into the lofty standards of academia. Many institutions are resting on their reputations. Trust, once lost, is difficult to regain. And they don't realize it, because of the effort to replace meritocracy with diversity.

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Scum human beings. Cyber criminals hacked into the records of Fred Hutchinson Cancer Research Center and are demanding money. In order to light the fire, they are swatting the cancer patients to make their lives miserable.

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7 January 2024

Today is January 7.  Time to burn (or salt) the Kadomatsu.

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The Lancet published a curious article stating that not using hearing aids when you're hard of hearing leads to dementia. Now they've retracted the article, saying that it was phony research. But that was only after other experts called them on it.

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Someone broke into the Seattle Betsuin and burned it much of the interior. Documents dating to 1901 were destroyed, as the arsonist chose to start the fire in the archival area.
Seattle can't get rid of homeless encampments. They keep coming back.

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Looks like no progress is being made regarding the Shigella epidemic in downtown Portland. It's probably on buses and other public transportation. On park benches and other things that the homeless touch. The city was more concerned about COVID-19 than they are with this. What's it going to take to get Portlanders to do something? Or demand that city leaders stop sitting on their hands about the homeless?
And the city can't get its beloved statues back because some DEI official things that restoring them "undermines an equity-driven process". "Equity" is one of the main reasons nothing gets done around here. Diversity is not our strength.

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Care is super expensive at OHSU. Things shouldn't be costing this much, but hey, someone's got to pay for all those higher nursing salaries. And soon, the advanced practitioner salaries. This lady should have gotten Medicare supplemental insurance, which would have taken care of what Medicare didn't cover. And I think OHSU expected that this would be in place. 
a quick search of the internet shows that Prevnar 20 is cheaper elsewhere, though how much cheaper varies. GoodRX.com lists it for $270 at various pharmacies. A list maintained by the U.S. Centers for Disease Control and Prevention shows Prevnar 20 has a private sector cost of $253.21. And the Walgreens on Northeast 33rd Avenue in Portland offers it for $307.99, with no charge for the jab.

Davis’s shot is just one of thousands given at OHSU, but her bill raises questions about a health care provider that will become the largest in the state—and the biggest employer in the Portland metro area—if regulators allow it to buy crosstown rival Legacy Health.

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NYT filed a complaint against Microsoft and OpenAI. This will be interesting to watch. If the NYT wins, then it's basically saying that A.I. can't be trained on anything, because you never know when someone will claim that they need compensation. Copyrighting intellectual property is getting to be really difficult to defend now, with so much being derivative on something else. Only the lawyers win. Japan's approach makes more sense.

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Another article describing amyloid deposition in the muscles of those with LongCOVID.  And this article from a few days ago reports other findings of LongCOVID but focuses on blood abnormalities, and does not mention amyloid. Nice that there are more publications on this condition lately.

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Veterans have to face endless delays for their cancer treatment due to delayed pre-approvals. With all the billions going overseas to support other countries, can't we give the veterans' doctors the benefit of the doubt and automatically approve diagnostics and treatment?

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More patients are losing trust in their primary care physician. Not only did this stem from the coronavirus epidemic debacle, but doctors are increasingly employees of hospitals and business-owned clinics. Freestanding clinics, owned by physicians, are getting to be rare now. So every doc must spew the party line. The narrative. Or be disciplined or let go. Physicians are acting like employees now. And they have no control over employees, who are often unionized. They don't have anything to do with billing problems or scheduling delays. The changes started with Obamacare.

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Wrong Axios, it's not because prices are too low. It's because drug companies want to maximize profit. Low supply costs from overseas sources allow them to maximize what they get from sales. It can be done in the U.S., and prices don't have to rise if the middlemen would just take lower profits.

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6 January 2024

Holographic camera turns any window into an invisible camera. Could this tech be abused? I could see some disadvantages to being able to turn any glass plate into a camera. Yes, it could streamline some things, especially in the automotive world, but there are definite potential privacy issues.

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Zosurabalpin: a new macrocyclic antibiotic. Highly specifric for carbapenem-resistant Acinetobacter baumannii, so there is still a need for other resistance-overcoming antibiotics. Mechanism is novel: works by inhibiting a bacterial protein complex called LptB2FGC, which prevents the bacteria from synthesizing its outer membrane.  FDA-approved.

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Brain tissue on a chip achieves voice recognition. Now we're getting into sci-fi territory. Specialized stem cells were grown into neurons that formed a ball called an "organoid". Electrodes were hooked up, and responses were decoded using machine learning algorithms. They call it "Brainoware". And it recognized the voices of eight subjects with an accuracy of 78%.  This may be the start of real artificial intelligence.

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600+ nurse practitioners at OHSU want to unionize. NPs were brought on as a cost-savings over paying doctors. Now since doctors have been hesitant to unionize, I wonder if the pay of NPs will be higher than that of the research doctors, who typically don't have as much clinical obligations, and get pay off their research grants.

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Yeah we already knew this. Number of people moving to Oregon plummets, U-Haul data shows. So the rest of the poor slobs who can't leave will have to pay more taxes to keep the government in business.

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Now there's data. When hospitals are taken over by private equity, hospital-acquired adverse events increase.

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Insight as to the cause of Sudden Infant Death Syndrome. It seems that the babies have seizures. Next step is to figure out why this happens.

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Even paper straws are problematic. "Forever chemical" plasticizers are the problem. Only metal straws were safe. But they're too expensive, and we'd have streets littered by metal straws, anyway.

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How well are existing parking garages able to handle modern vehicles?. Look at how heavy those EVs are.
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5 January 2024

A survey of 2700 A.I. researchers found that there is a 5% change of humans becoming extinct because of A.I.  But don't worry. The folks at Google DeepMind have written a robot constitution that should prevent this from happening. Whew! I was worried.

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HKDC1 signaling prevents senescence in mitochondria and lysosomes, which may help attenuate the aging process. I wouldn't read too much more into that right now. The article's headline is a bit sensational.

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ChatGPT fared poorly in making a correct diagnosis of 100 pediatric cases.  Still not ready for general usage. The article does not provide information about retrieval-augmented generation (RAG), which is a necessity now. This technology is still in development, and requires knowledge of optimal segmentation, and the selection and configuation of vector databases. Maybe the good doctors didn't do any of this.

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All those monoclonal antibodies (aducaumab, lecanemab, and donanemab) against amyloid-β are not very effective. But with ultrasound treatment to break down the blood-brain barrier, they might be. More details here.

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The reality of Danish healthcare and economy. Everything comes at a price. I doubt this system would work in America. This article is good to bookmark to show people who think that socialized medicine will solve our healthcare delivery problems.

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Free bulk photo compressor. I use Optimzilla, which works well.

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FDA authorizes Floridians to purchase drugs through Canadian pharmacies. This is great for now. Hope other states do the same.

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ZeroHedge has an interesting article about Bidenomics. It contains this interesting statement that "not only has all job creation in the past 4 years has been exclusively for foreign-born workers, but there has been zero job-creation for native born workers since 2018!"  All those new jobs that Biden brags about have net gone to foreign-born workers. For native-born Americans, the net jobs created has been a wash. It's really that bad. Does anyone really want four more years of this?
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Ohio Gov Mike DeWine Signs ‘Emergency’ Executive Order Banning Transgender Surgeries for Minors After Vetoing Similar Bill.  He saw the light, I guess. Bravo for him for seeing the light at last.

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4 January 2024

What a waste of time and money. Federal judge in Oregon denies efforts to dismiss climate lawsuit filed by young people. If they're really serious about this, they should sue China and India. This makes about as much sense as banning plastic straws – another child-initiated policy. The kids are victims of shoddy science reporting, which is getting to be so common these days. 

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23 and Me says that it's the customer's fault for the security breach, since they didn't change their passwords. What crap.

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OHSU's Dr. John Hunter is stepping down. He's a great guy, and it's too bad that he's leaving the leadership circle. Boy, they really need someone like him. Big loss for them.

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