25 July 2025

Do Dogs Know Who’s Good or Bad? Just watching how humans interacted with other dogs and who gave food, doesn't determine a dog's opinion.  It has to see for itself how the human is.

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Some insights into browser fingerprinting.  If you really want to resist fingerprinting, use the Mullvad browser with Tor. NordVPN makes this easy. Remember, practice privacy.

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It's starting. In West London, you can't build new houses because their grid can't support anything else above their datacenter. Power demand is too high. Neither wind nor solar is going to cut it.

And in Sacramento, they use smart meters to spy on residential power usage. Too much, and they call authorities to check you out. Real "smart", huh?

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Shall we let the Internet die and start over? Nah, we'll just build something else that will go to crap once we allow anyone to use it. But yeah, the Internet is a den of thieves now. Not as nice and fun as back in the old days.

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Lately people have been reporting the two coding tools, Replit and Gemini CLI, have been deleting files without permission. This is a big flaw, as one company discovered to their dismay. One guy reports that even Cursor feels the need to delete files, too.

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Japanese scientists feel that they are on the verge of repairing the genetic abnormality that characterized Down Syndrome. This is tricky because the problem is not a mutation, but just an extra copy of a chromosome. You don't want to destroy an entire chromosome. They'll be using allele-specific engineering.  They've had success with fibroblast cells. It probably won't fix adults, but perhaps it can catch things at a far earlier stage.

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This is the longest and most intricate Rube Goldberg chain reaction video I've come across. Watch The Pancake Flipper.

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This is BBC's hilarious racism awareness video, showing contrived situations where microaggression happens in the workplace. White people don't talk this way. Sheesh, the demand for racism outstrips the supply, I guess.

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Trump has issued an EO declaring that the homeless be removed off the streets. Not only that, but he recommended that asylums be brought back. I read that the NGOs in the Homeless Industrial Complex are upset. Their business model will dry up.  Too bad. But leaving the drug-addled homess to fend for themselves is not compassion.

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Oregon is going to proceed with the Rose Quarter road project anyway, even if there is no funding. Unions members gotta work, I guess. They're probably hoping that somehow they'll get the funding they need. Others are wondering why we're not fixing the potholes and damage in the roads first.

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And I like this characterization of AI: It's like an over-confident friend that doesn't admit that he's wrong. And doesn't learn from its mistakes. Because that would require retraining, which is too expensive and time-consuming.

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24 July 2025

Puhleeze. Is This the End of Google As We Know It?  How many articles have been written with this title? It's like "the walls are closing in."  Google will survive. 

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Earth's days are getting shorter by a millisecond. Does it really matter? I wouldn't notice it. But I guess the people who keep track of these things will.

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Fragmentary Latin inscriptions can be completed with AI. The technology is finding its uses. It's amazing to be able to deduce missing text from broken pieces of writing.

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Wow, I feel sorrry for the lower level employees at Windsurf.  The company didn't exactly reap the riches that startups typically do. It's becoming clear that low-hanging fruit has been picked. You gotta be smart and have something to add to technology to win the pay. Just being a low-level employee doesn't mean you'll get super rich. 
"Windsurf and others are really bad examples of founders leaving their teams behind and not even sharing the proceeds with their team," wrote storied investor Vinod Khosla on X. "I definitely would not work with their founders next time."
Here's more on this debacle: Looks like the engineers who went to Google are getting screwed, too. There were no winners here. It's not that easy to create wealth out of thin air in the AI age. It's not the dotcom world. 

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Proton is starting to move out of Switzerland due to their new laws that reduce the kind of privacy that Proton promotes. It's too bad, but Switzerland's new laws look pretty bad. But why is Proton going to the EU for protection? They're not known to be privacy-friendly either. 

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GLP-1 drugs may cause kidney injury if you get dehydrated. Sounds like acute tubular necrosis to me. You can recover partially from it, but sometimes not.

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Can you run a business solely relying on AI?  Apparently not. Anthropic decided to test this with Claude, and apparently it was "hilariously bad". And some have put down some good reasons why AI will not take most human's jobs.

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So does gold even have a melting point? It was thought so, but it's clear that it depends on how the heat is applied. It's crazy how we're still discovering some things about basic science.

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Using external CSS when designing a webpage can make seconds of difference, especially if your connection is not fast. I'm not sure it's worth cluttering up your code with all that CSS, which can take up a lot of space. I'll put up with the extra few seconds of loading time for now. 

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SurgeAI claims to have found out what datasets Anthropic trains its models on. This is ordinarily a trade secret, but it seems that Anthropic didn't care too much. They're sort of denying that it's authentic, but who knows?

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Supposedly, Washington state is in their worst budget crisis.  Kinda like Oregon, except they have a lot of billionaires and millionaires – way more than Oregon. They have much of the money they really need, don't worry. They just don't want to change what they spend it on.
Like Oregon is supposedly short of money, but they allocated $15 million for non-citizens. How does it feel to have to pay more tax and have services cut?
Even California is no longer paying for illegal alien's legal defense anymore. Why can't Oregon and Washington learn from this?

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Palisades residents are discovering a new horror, as they try to recover from January's fire – squatters. And the police aren't helping. What a nightmare.

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The resulting $147,187 incentive payment for Rex Kim, the chief investment officer, boosted his total pay to $663,271. Michael Langdon, then the director of private markets investments, received $123,105, lifting his total pay to $533,459. 
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23 July 2025

Are we in an AI bubble? Someone else wondered about this, too. I've wondered about that myself. AI benchmark achievements have been remarkable, but really, would we be surprised if we developed a search algorithm that was able to retrieve things more efficiently than the old TfIdf or PageRank type algorithms. AI chatbots do seem to do much more, but ultimately that is how they're trained. We're slowly giving them more reasoning capacity to handle more complex problems, but they can't truly replace humans doing complex tasks just yet. Fact retrieval is one thing, but I am skeptical about decision-making. Plus, to approximate or surpass human thinking, we need datacenters that would need to be huge, but also have energy demands we couldn't possible meet for long.

Anthropic also posted results that suggest that too much thinking makes LLMs dumb. So they can overthink things, just like humans, I guess.

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Proton has developed a privacy-focused chatbot called Lumo. This chatbot uses open source LLMs, so everything can stay enclosed within their system. It can provide RAG if you turn on the Web Search tool. It was last trained in October 2023, however, so from then on, everything is web search.  And it will probably still be subject to hallucinations, like all models.

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Google's AI bot and OpenAI's bot scored gold medals at this year's International Math Olympiad. But the top scores still went to humans. That's good for now, I guess.

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Amazon buys AI wristband that listens to everything you say. Really, who would want something like this?

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I saw this about the unexpected brain boost that comes with muscle-building exercise. Then I was reminded of this post by Scott Alexander about what nootropics really worked, and which were just placebo. I was surprised that weightlifting scored so high. Only dextroamphetamine and amphetamine/dextroamphetamine were better.  Does muscle-building really work?

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Duh. Having a higher income boosts your chances of finding a romantic partner.  Heh, this is literally the only hope for less-than-handsome men. It's also probably a factor in the drop of global fertility – the income disparity has been increasing, especially in the U.S. Look at the Gini coefficient.

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More than half of adults admit to peeing in swimming pools. That's where the chlorine smell comes from. Pristine pool water shouldn't smell like that.

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Wow, you can have a kidney transplant and not have to take immunosuppressants. Injection of stem cells can induce immune tolerance.

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Oregon’s seasonally adjusted nonfarm payroll employment declined by 4,300 jobs in June.  No surprise here. Business are closing or fleeing Oregon in droves, it seems. The government has relied too heavily on taxes and federal subsidies to keep the state running.

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Whoa, if this is true, the United States is giving out way too much welfare money. Eliminating the $200 billion spent on remittances would be great savings for the country – money that we shouldn't have to be spending.

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22 July 2025

How things stand 6 months after the Palisades fire. You basically have a neighborhood where people just gave up. Lesson learned. You can have insurance and think you're prepared. But you're not. There's no protection against a total house fire when you live in a Blue state, especially in a Blue city.

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"Unfortunately, I think 'No bad person should ever benefit from our success' is a pretty difficult principle to run a business on," Amodei wrote in an internal Slack message to staff, obtained by WIRED. "This is a real downside and I'm not thrilled about it."
There is a word for this – realpolitik.  But this is how power gets into the wrong hands. Because of people like Amodei. It's really sad that the West doesn't have enough billionaires that could have shepherded this technology.

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What factors cause lung cancer in never-smokers? Two things: second-hand smoke and air pollution.  There are signature mutations that are seen with different causes and in different locales, so you can almost predict what causes the lung cancer.

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Yes! Yes! Are Hospital Acquisitions of Physician Practices Anticompetitive? This was one of the worst things that came out of Obamacare. Hospitals were handed gobs of money and it became very hard for individual physician practices to compete against them. In Portland there were new glass-and-steel monstrosities that came up. Meanwhile, doctors sold their practice and became employees subject to the whims of hospital administrators, and in OHSU's case, the governor (Kate Brown).

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Will AI take people's jobs away? Here's one guy's take on this.  He thinks that there will just be changes made, new jobs and some reshuffling. One of the points that he uses to bolster his argument is this graph.

Notice something? The author says that the drop in jobs occurred before AI became a thing, around 2012, so it's not just AI. But who was president during that time? What was set in motion during that time that might have led to a loss of jobs? It wasn't AI, but I think the presence of AI now will make this worse.

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Seattle has got the nation's highest inflation rate, according to WalletHub. Not only do things cost more, but services cost more, especially as the minimum wage has increased again. Luckily, there is Bellevue and surrounding municipalities.
And Oregon was ranked by CNBC as the most expensive state, mainly due to housing. And Portland wants a 75% increase in the property tax, to support parks, trails, community centers. 
 
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Intel Raptor Lake hardware crashes in the heat wave. The last thing Intel needs now is that their chips are defective and underperforming. It's like a Boeing situation. People will ditch Intel for something else.

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Omega-3 fish oils can reduce aggression in people by up to 28%, whatever that means. I don't think fish oil is going to make a difference.

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Humans can be tracked based on how their bodies block WiFi signals. Yeah, basically they trained an AI model on a dataset and got predictability. We see so much "science" like this.  Just because you do that doesn't mean it can be used generally.

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Why government-funded media is a bad idea. It started with noble intentions, but people are people, and leftists took over.

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Pretty soon, the choice is going to be AI or A/C. AI energy demands will mean less electricity for the rest. We cannot rely on low energy density sources like wind and solar. It's just not going to cut it. We need petroleum- or nuclear-based electricity. It's clear to anyone who has studied energy production. 

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21 July 2025

Supposedly just listening to this Mozart piece (K.448) enhances your working memory.  I would get distracted by the music and forget what I was supposed to be doing.

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Here's all the Epstein stuff that has ever been released. In case you were interested.

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Ancient DNA origins explain why the Finnish and Hungarian languages are so different. I always wondered about that, especially the Finnish language being so unlike that of their German neighbors.

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PERS is in trouble.  Too much money in illiquid private equity. All locked up in real estate, hedge funds, commodities. Who's in charge anyway? 
To make ends meet, they’ve also sold a swath of private equity investments – $4.5 billion worth in recent years – at a discount to their reported value. Officials won’t say exactly what those discounts were. Most of their dealings with the funds are exempt from disclosure under the state’s public records law. 
Ouch. This is not good fiduciary duty. Update (22 July 2025): more here.


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Look at how Oregon employment compares with other states. Not favorably. What do you notice about the leadership in the highly employed states?

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This is Oregon collegiate education. What a joke. Can't pay off your student loan? Gee, I wonder why, college grad.

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Telomir-1 fully reversed epigenetic silencing of the STAT1 tumor suppressor gene in aggressive prostate cancer cells, outperforming Paclitaxel and Rapamycin. For prostate cancer, they usually use docetaxel and rapamycin isn't standard therapy. But still, targeted therapy being better than a taxane is remarkable. Maybe I should get me some TELO stock. It sure shot up last Friday.

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Chinese scientists figure out how to do photosynthesis without plants. Turn methanol into sucrose. The title suggests it's CO2 to sugar, but you gotta turn the CO2 into methanol first. Boy, the Chinese are sure solving a lot of life's problems lately. Is it for real, though?

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What do you think?  90% of all the scientists that ever lived are alive today.  Were things better when it was harder to be a scientist?  Maybe it's like being an artist today – we have so many, and the standards are much lower. That's why we see so much crappy art.

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20 July 2025

Prexist is supposed to check to see if your startup ideas has already been though of before.  What a great way to get people to divulge what they are planning to do. It's just like when people who submit possible URL names to register. If you found a great name and don't purchase it, it might be gone later if you change your mind and decide to go back and register it.

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Apple may introduce their foldable iPhone next year. Sigh. Apple used to be able to keep all kinds of secrets when Steve Jobs was alive. Now, it's like Tim Cook doesn't care. Insiders find out and leak all the time.

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Starting next year, you'll have to pay for a permit for anything you bring to the water to float on. So desperate they are for tax money.
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19 July 2025

Mitochondrial function may be the key to why we sleep. 

Here we report that transcripts upregulated after sleep deprivation, in sleep-control neurons projecting to the dorsal fan-shaped body (dFBNs) but not ubiquitously in the brain, encode almost exclusively proteins with roles in mitochondrial respiration and ATP synthesis. These gene expression changes are accompanied by mitochondrial fragmentation, enhanced mitophagy and an increase in the number of contacts between mitochondria and the endoplasmic reticulum, creating conduits for the replenishment of peroxidized lipids. The morphological changes are reversible after recovery sleep and blunted by the installation of an electron overflow in the respiratory chain. 

Sleep, like ageing, may be an inescapable consequence of aerobic metabolism.
So it's all in the mitochondria, then. The paper still doesn't explain the why. Why does this need to happen? Why can't we replenish peroxidized lipids all the time, instead of just while we sleep?

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Meta has poached two key AI experts from Apple. Why does it have to be Meta? Why couldn't it be some less invasive company? I just don't trust Zuck to own the next generation of AI developments. 

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Tirzepatide seems to slow breast cancer growth. Well, since breast cancer growth is associated with obesity, it's not surprising that this happens. Elimination of obesity will likely improve lots of things. Maybe your career, your love life, etc.

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Diamonds are not worth the expense anymore. Even De Beers has thrown in the towel. It was a good run while it lasted. Progress is a good thing, right?

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Dead EV batteries can be recycled now. That's some good news.

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Scientists are developing a universal cancer vaccine that can kills "any tumor". This seems to be the wrong approach to me. I would rather we figure out how to put multiple copies of the TP53 gene into the genome. Seems to make better sense to me than subverting the immune system to attack some onco-antigen.

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Eating eggs is good for your cholesterol now. It doesn't cause harm like conventional wisdom has said. Nutritional wisdom always seems to change radically every ten years or so. Things that were considered good are now bad, and vice versa.

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Erythritol is now linked to brain injury and strokes.  Shouldn't we take this off the market? Are you seeing this, RFK, Jr?

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Space travel can permanently damage your eyesight. There is a condition called Spaceflight Associated Neuro-ocular Syndrome, and it causes edema of the optic nerve, due to microgravity. Once it causes damage, it is irreversible.

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Lost cause. Voice actors demand that AI regulate voice generative AI.  Yeah, that's not going to happen. You're not that special, and this is going to go the way of the buggy whip. Sorry, but it was fun while it lasted.

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Most old folks, like this ronin, have a scar on their arm, and we were told it was a smallpox vaccine scar. But wait.
Many foreign-born persons have received the bacille Calmette-Guerin (BCG) vaccine for TB disease. This vaccine is administered at birth in many countries outside of the U.S. to prevent childhood tuberculous meningitis and miliary disease. BCG leaves a scar like the smallpox vaccine. But it doesn’t protect against smallpox.
So if you have a positive TB test, it might be from the BCG you got, not from actual tuberculosis.

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OpenAI has scored well enough on the International Math Olympiad to have won the gold medal. Who needs MIT students anymore, right?

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Yeah, crime rates do go up around overnight homeless shelters. Thought so.

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Why is Oregon still blaming the pandemic for poor school performance? The rest of the country has moved on. Man, the coronavirus epidemic was five years ago. Enough, already. Look in the mirror to see who deserves the blame.

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Portland city government force the Gateway Fred Meyer to close.
Also since last year, Portland went on a property tax increase binge as well as enacted a 10-cent gas tax hike.  Just months ago, Portland pushed through a billion dollar property tax hike for schools.   Just weeks ago, Portland City Hall jacked up parking fees and doubled the Uber tax.

A full year of non-stop financial blows both from within by workers and from the outside by politicians hurt the Gateway Fred Meyers too much.

Now those union workers don’t have a job.
Good going, folks. The Doom Loop continues.

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18 July 2025

Amazon is struggling as the cost of AI intensifies. Everyone acts like providing AI for free is so easy. The public is now conditioned to think that it's going to be like online search. But supporting those AI datacenters is not cheap. Something's gotta give. I would have thought that profits from Amazon retail would help support this, but I guess not.
Heck, even OpenAI is going to Google for support to keep their systems going. I guess Microsoft hasn't been able to deliver. What's going on?

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I have not heard of New Weird fiction before. But I like it. I like Old Weird, too, but they never classified those books as such. There should just be Weird Fiction or Disturbing Fiction. I don't think Powell's Books is using this category, though.

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Nice review article on reserveratrol. It's probably not the lifespan extender everyone was hoping it would be, but that anticancer, anti-inflammatory and neuro- and cardioprotective effects are still beneficial. I didn't know resveratrol had activity against Staph aureus and rotavirus diarrhea.

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Here's an interesting fact about global life expectancy over the centuries:

So progress has been made.
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A lot of people are upset about the loss of NPR, but it's important to remember what kind of a station it had become. I got tired of hearing the left-wing propaganda, too, and hated that it was supported by tax money. I remember the Jay Leno joke about listening to the radio to get caught up with what was going on regarding the war in Iran. In the morning he'd listen to Fox News and heard how we were winning, and then going home he'd listen to NPR and heard how we were losing. We don't need paid propaganda. NPR used to be fun, with Car Talk, Thistle and Shamrock, and Prairie Home Companion. Then it slowly became politicized and all the fun shows were just ways to poke jabs at conservative thought, while ignoring liberal idiocy. Not sad to see this go down finally.

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Oregon unemployment continues to increase. No surprise.

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Could it be this simple? 
The new results show that some gut bacteria, in certain states, produce imidazole propionate, a simple molecule with six carbon atoms, eight hydrogen atoms, two nitrogen atoms, and two oxygen atoms (C₆H₈N₂O₂). This compound enters the blood, interacts with immature white blood cells, and triggers an inflammatory reaction in the arteries, which promotes the buildup of fatty plaques.
Well now at least we have a target. But fighting atherosclerosis may look quite different. Perhaps we can have rich food again.

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Another marker of Portland decay.  Well, the Broadway Tower is going back to the lender.  The ground floor restaurant has closed. What will become of the empty building?

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What's behind the GenZ Stare? I've seen this look, and thought maybe it was just me. It's basically a look that says "I don't give a s**t about what happens."

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More than half of teens use chat AI for emotional support. Not only is it sad that this is happening, but think of the privacy concerns. Those companies have a treasure trove of information on these kids. Maybe it'll come back to haunt them later.

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17 July 2025

Why is ChatGPT driving some people insane? So ChatGPT Psychosis is a thing now?

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Another report on California's SB 549. People are waking up. People voted overwhelmingly for Senators Ben Allen and Sasha Perez. I guess they really do deserve what they voted for.

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Portland is becoming a socialist city. This is why nothing improves and the city spirals downward.

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Oregon hospitals are going to get hit harder than most states. The old Tuality Hospital acquisition is now coming back to bite them. What an albatross it is. And Providence has their Seaside hospital, which will be a drag. All the hospitals will likely see a downturn now, just some worse than others.
Oh, and more Legacy nurses are joining the union. Just the thing to add more headaches to Legacy administration.

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"...A Portland Business Journal report notes that employment in Oregon’s burgeoning nonprofit sector now threatens to surpass the state’s total manufacturing employment base."
"The state’s nonprofit workers earn more ($70,596) than the average private business employee ($69,905)."
So Oregon's main economy will soon be NGOs. But as "the non-profit sector is heavily reliant on grants", this is likely to end soon. This is where Oregon's budget goes, and why people often say "What happened to the money?" when nothing changes.

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Oregon news media is drying up. Modern journalism doesn't pay anymore. You can tell by the quality of articles you see these days.

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Mayor Keith Wilson is sticking to DEI, even though it will cost the city around $387 million, because he refuses to eliminate racist and woke policies and sanctuary status. OK, then, you made your decision. Watch the city go down.

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Oregon state employees are going to get AI training. It doesn't say what they will learn, but I bet it will be just how to use ChatGPT.

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16 July 2025

What Caused the 'Baby Boom’? What Would It Take to Have Another?  It's not too difficult. People need to be financially comfortable. It's hard to feel like taking on marriage when you're financially struggling and have low self-esteem. Plus, the dating pool is crazy these days. Saw this on X today:

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What's contributed the most to the obesity epidemic? It's the food that people eat. Avoid ultra-processed food. But improving muscle bulk wouldn't hurt either. 

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Half of homeless people have experienced traumatic brain injury. I'm not surprised. And we're supposed to let these people make decisions for themselves? For a lot of them, this is how they got to be where they are. The sooner it is realized that we need to make the decisions for them, the better we'll solve the homeless problem.

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AI will cause harm, but it's worth it. That's what Jensen Huang says. And society will have to get used to robots everywhere. Gotta get American manufacturing going, too. Agree fully. It's not going to be easy but it will be necessary. But we also have to solve the energy problem.

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This study was promoted as showing the caffeine prolonged survival. Indeed, the authors conclude that caffeine is beneficial for chronological lifespan through AMP kinase, but it also synergizes with other genotoxic agents to increased DNA damage sensitivity (huh?). I'm OK with the former, but do I want the latter. Caffeine inhibits TORC1, just like rapamycin, and so that may be how it prolongs survival. It's not clear to me what the impact it's effects on DNA damage are. I'll still drink coffee until their figure it out, though.

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Japan recently set the record for the fastest Internet speed – 4 million times faster than U.S. broadband. I still chuckle remembering that some wag publicly states that 9600 bps was the theoretical limit to how fast the Internet could be. Yeah, sometimes it pays to ignore experts.

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The aluminum adjuvant in childhood vaccines was shown to be harmless. Well that's good, because I got it.

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If you ask Grok to show you a picture of a group of average Americans, it consistently shows you what looks more like average Baltimore. Or Detroit. That's the way it's been trained, I guess.

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What age is old? It seems to be getting later. That's great news for this ronin, who is probably considered old by anyone's definition.  Shikata ga nai.

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Asians are avoiding traveling to the U.S. now. So ironic – they have little to worry about. Meanwhile the U.S. will get unbridled in-migration from the Middle East and Central America. They're not scared.

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I agree. If you want facts, Perplexity is probably the best chatbot to use.

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People can't stop talking about the Intel layoffs, which will hurt Oregon. Someone pointed out that Multnomah County has the hospitals and Washington County has Intel, Nike and the datacenters. Everyone is hurting, though, but it may be that they will hurt differently, and at different rates. Each will pursue different strategies. I think the hospitals will be the most vulnerable, however.

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A great joke has been played on those whose homes burned down in the Palisades fire. Their tax money will be used to build low income housing in their neighborhood. How's that for adding insult to injury?

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The Fred Meyer in the Gateway district is going to close. They aren't saying why, but we know. More unemployed that the state has to support. Decreased tax collection for Multnomah County. Another empty building that will be a blight and a target for graffiti and vandalism. 

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