Very interesting study, although it was just done on one subject.
Researchers found that factors such as decreased or fragmented sleep had negative effects on memory and brain connectivity that lasted two weeks. Also, physical activity helped to improve memory and brain connectivity.
Firstly, results from sleep studies suggest that the amount of accumulated awake time is associated with the performance in attentional tasks, thus making attentional maintenance more variable and inconsistent. Secondly, such variability is manifested in errors of omission (i.e., failure to respond in a timely manner or attention lapses) and errors of commission (i.e., response to stimuli that are not present). These errors can be detected by specialized, reliable, and valid tests such as the Psychomotor Vigilance Test which is simple enough to avoid learning effects and is sensitive to sleep loss. Thirdly, brain studies have shown that sleep deprivation (SD) is positively correlated with decreased activity in the prefrontal cortex (PFC), visual, parietal, and premotor areas during attention tasks.
Firstly, sleep and physical activity are known to affect working memory. While sleep deprivation causes deficits in working memory performance, physical activity improves working memory function.
Regression models show diverse associations of external factors such as sleep, activity, mood, and physiology with brain network dynamics in the default mode, fronto-parietal, cingulo-opercular, and somatomotor networks. Time-lagged cross-correlation analyses suggest that the associations between brain connectivity and these external factors extend beyond the previous day, spanning up to 15 days in the past, possibly reflecting a more prolonged and sustained relationship between external factors and neural processes.
Fragmented sleep increases subjective fatigue and deteriorates inhibition, even when the total sleep duration remains unchanged. Therefore, it is not surprising that supporting our hypotheses, our results show that restlessness is strongly associated with changes in brain connectivity during sustained attention tasks. Indeed, repeated disruptions in sleep are known to progressively reduce attention, with vigilant attention deficits building up across consecutive days of sleep restriction in a dose-dependent manner.
Sleep also plays a crucial role in efficient functioning of working memory. We observed that longer sleep and more interruptions during sleep are associated with greater integration of the DMN and FPN. However, the effect of sleep duration on working memory does not seem to occur immediately but is observed after a 2-week delay.
I never understood why in medical internships, doctors on call were forced to function and make critical decisions while sleep-deprived.
Sleep deprivation causes cortical thinning. The doctors' precious brains were being destroyed.
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I love
this advice that Florida gave to EV owners affected by the hurricane floods:
Park your EV 50 feet away from any structure or other vehicle. Storm surge can harm the battery and increase fire risk.
Yeah, right!
––– 凄い –––According to the data published by the Oregon Department of Financial Regulation, 18 PBMs received $287,583,732.64 in rebates and payments from manufacturers last year.
A majority of the payments, $283,727,097.34, went to insurance companies — while $2,236,217.76 (0.8%) were passed on to consumers. The managers retained the remaining funds (99.2%) as revenue.
As middlemen providing no real value to consumers, they insert themselves between the doctor and the patient and skim off money...lots of money.
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Hemophilia B can now be treated with a one-weekly injection. It's the first antitissue-factor pathway inhibitor. Pfizer already secured approval for
Beqvez, a one-time gene therapy for patients with hemophilia B. But some may prefer not to go this route.
––– 凄い –––Interesting infographic about the different concerns that Republicans have compared with Democrats:
It's interesting that Democrats claim to care about democracy, when so much of what they clamor for (removal of free speech, Second Amendment rights, packing the Supreme Court with judges who promote their ideology when events don't happen their way, eliminating the Electoral College, restricting a presidential candidate to one of their elite's choosing, rather than a democratically elected one) is not imbued with democracy.
––– 凄い –––This is what happened when Norway increased taxes, no doubt trying to make their millionaires and billionaires pay their "fair share":
––– 凄い –––Things aren't looking good for Hawaii. This excerpt is from a newsletter I get from the Stott Real Estate property management company. Take a look:
In retrospect, Gov. Ige really destroyed the state with his policies. And Hawaii will still vote for the same politicians, no matter what. What will it take for those people to learn?
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