Interesting.
Breast cancer cells stimulate sensory nerves to release substance P, which interacts with the tumor's TACR1 receptor, killing them, but the dead cancer cells' single-stranded RNA (ssRNA) stimulates the tumor cell's toll-like receptor, TLR7, which
activates a pro-metastatic gene expression program. Kudos to them for not stopping at the first step and figuring out what it was that produced the end result of metastatic stimulation. The good news is that aprepitant can stop this process, and oncologists are already giving it with very nauseating chemo regimens. The bad news is that ssRNA can come from other sources – such as the COVID mRNA vax. Do you think all the side-effects of RNA injection have been really studied well?
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Google, Microsoft and Amazon are taking a different tack with AI startups. Instead of buying up the startup, they just license the technology, hire all the top employees, buy out the shareholders, but the founders and investors are no longer in control. They'll still get money for their efforts, but it's not quite the same. Maybe this is a better way? This is because of increased scrutiny over monopolization.
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Practice works, but genes work better. This piece says that you can work hard and practice a skill, but innate talent will be better. But better to practice than not practice. So "choose niches which are so small or esoteric that there is less competition, or lower expectations accordingly." Is this something we didn't already know?
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Taiwan Semiconductor finds that what works in Taiwan doesn't necessarily work in Arizona.
Jefferson Patz, an engineer fresh off a master’s degree from the University of California, San Diego, went to Tainan in 2021 for 18 months of training shortly after he joined the company.
“Oh, my gosh, people work hard,” Mr. Patz said. He recalled that this initial impression had given him a strong sense of what it took to succeed in the industry.
After returning to Arizona, Mr. Patz said, employees were expected to pitch in with work outside their job descriptions because construction of the facility was behind schedule.
This approach did not sit well with everyone.
Taiwanese work ethic ≠ American work ethic.
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We've seen this time after time. And the public still falls for this.
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Private equity firms spent $505 billion on health care acquisitions between 2018 and 2023. Financial infusions may augment resources for care. However, firms have sometimes sold acquired hospitals’ land and buildings, repaying investors with proceeds and burdening hospitals with rent payments for facilities they once owned. Financial outcome of private equity hospital acquisitions and effects on patient care require further study.
Looks like they buy assets for cheap, squeeze whatever juice there is, and
hospitals are left with less than they had before.
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“The whole restaurant industry has never recovered post-COVID,” he said.
“Recovery to where you were before is nonexistent. Everybody’s habits are so different now.”
Oregon government didn't do anything to help. Just raised taxes and added more fees.
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